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Identification of low molecular weight pyroglutamate A{beta} oligomers in Alzheimer disease: a novel tool for therapy and diagnosis.
Wirths O, Erck C, Martens H, Harmeier A, Geumann C, Jawhar S, Kumar S, Multhaup G, Walter J, Ingelsson M, Degerman-Gunnarsson M, Kalimo H, Huitinga I, Lannfelt L, Bayer TA. Wirths O, et al. Among authors: harmeier a. J Biol Chem. 2010 Dec 31;285(53):41517-24. doi: 10.1074/jbc.M110.178707. Epub 2010 Oct 22. J Biol Chem. 2010. PMID: 20971852 Free PMC article.
Sortilin-related receptor with A-type repeats (SORLA) affects the amyloid precursor protein-dependent stimulation of ERK signaling and adult neurogenesis.
Rohe M, Carlo AS, Breyhan H, Sporbert A, Militz D, Schmidt V, Wozny C, Harmeier A, Erdmann B, Bales KR, Wolf S, Kempermann G, Paul SM, Schmitz D, Bayer TA, Willnow TE, Andersen OM. Rohe M, et al. Among authors: harmeier a. J Biol Chem. 2008 May 23;283(21):14826-34. doi: 10.1074/jbc.M710574200. Epub 2008 Mar 24. J Biol Chem. 2008. PMID: 18362153 Free article.
Novel APP/Aβ mutation K16N produces highly toxic heteromeric Aβ oligomers.
Kaden D, Harmeier A, Weise C, Munter LM, Althoff V, Rost BR, Hildebrand PW, Schmitz D, Schaefer M, Lurz R, Skodda S, Yamamoto R, Arlt S, Finckh U, Multhaup G. Kaden D, et al. Among authors: harmeier a. EMBO Mol Med. 2012 Jul;4(7):647-59. doi: 10.1002/emmm.201200239. Epub 2012 Apr 19. EMBO Mol Med. 2012. PMID: 22514144 Free PMC article.
The cellular prion protein mediates neurotoxic signalling of β-sheet-rich conformers independent of prion replication.
Resenberger UK, Harmeier A, Woerner AC, Goodman JL, Müller V, Krishnan R, Vabulas RM, Kretzschmar HA, Lindquist S, Hartl FU, Multhaup G, Winklhofer KF, Tatzelt J. Resenberger UK, et al. Among authors: harmeier a. EMBO J. 2011 May 18;30(10):2057-70. doi: 10.1038/emboj.2011.86. Epub 2011 Mar 25. EMBO J. 2011. PMID: 21441896 Free PMC article.
19 results