Wirths O - Search Results

1

Identification of low molecular weight pyroglutamate A{beta} oligomers in Alzheimer disease: a novel tool for therapy and diagnosis.

Wirths O, Erck C, Martens H, Harmeier A, Geumann C, Jawhar S, Kumar S, Multhaup G, Walter J, Ingelsson M, Degerman-Gunnarsson M, Kalimo H, Huitinga I, Lannfelt L, Bayer TA. Wirths O, et al. J Biol Chem. 2010 Dec 31;285(53):41517-24. doi: 10.1074/jbc.M110.178707. Epub 2010 Oct 22. J Biol Chem. 2010. PMID: 20971852 Free PMC article.

2

Lewy body variant of Alzheimer's disease: alpha-synuclein in dystrophic neurites of A beta plaques.

Wirths O, Weickert S, Majtenyi K, Havas L, Kahle PJ, Okochi M, Haass C, Multhaup G, Beyreuther K, Bayer TA. Wirths O, et al. Neuroreport. 2000 Nov 27;11(17):3737-41. doi: 10.1097/00001756-200011270-00029. Neuroreport. 2000. PMID: 11117482

3

Key factors in Alzheimer's disease: beta-amyloid precursor protein processing, metabolism and intraneuronal transport.

Bayer TA, Wirths O, Majtényi K, Hartmann T, Multhaup G, Beyreuther K, Czech C. Bayer TA, et al. Among authors: wirths o. Brain Pathol. 2001 Jan;11(1):1-11. doi: 10.1111/j.1750-3639.2001.tb00376.x. Brain Pathol. 2001. PMID: 11145195 Free PMC article. Review.

4

Intraneuronal Abeta accumulation precedes plaque formation in beta-amyloid precursor protein and presenilin-1 double-transgenic mice.

Wirths O, Multhaup G, Czech C, Blanchard V, Moussaoui S, Tremp G, Pradier L, Beyreuther K, Bayer TA. Wirths O, et al. Neurosci Lett. 2001 Jun 22;306(1-2):116-20. doi: 10.1016/s0304-3940(01)01876-6. Neurosci Lett. 2001. PMID: 11403971

5

Reelin in plaques of beta-amyloid precursor protein and presenilin-1 double-transgenic mice.

Wirths O, Multhaup G, Czech C, Blanchard V, Tremp G, Pradier L, Beyreuther K, Bayer TA. Wirths O, et al. Neurosci Lett. 2001 Dec 28;316(3):145-8. doi: 10.1016/s0304-3940(01)02399-0. Neurosci Lett. 2001. PMID: 11744223

6

Intraneuronal APP/A beta trafficking and plaque formation in beta-amyloid precursor protein and presenilin-1 transgenic mice.

Wirths O, Multhaup G, Czech C, Feldmann N, Blanchard V, Tremp G, Beyreuther K, Pradier L, Bayer TA. Wirths O, et al. Brain Pathol. 2002 Jul;12(3):275-86. doi: 10.1111/j.1750-3639.2002.tb00442.x. Brain Pathol. 2002. PMID: 12146796 Free PMC article.

7

Alpha-synuclein, Abeta and Alzheimer's disease.

Wirths O, Bayer TA. Wirths O, et al. Prog Neuropsychopharmacol Biol Psychiatry. 2003 Feb;27(1):103-8. doi: 10.1016/S0278-5846(02)00339-1. Prog Neuropsychopharmacol Biol Psychiatry. 2003. PMID: 12551731 Review.

8

No alterations of hippocampal neuronal number and synaptic bouton number in a transgenic mouse model expressing the beta-cleaved C-terminal APP fragment.

Rutten BP, Wirths O, Van de Berg WD, Lichtenthaler SF, Vehoff J, Steinbusch HW, Korr H, Beyreuther K, Multhaup G, Bayer TA, Schmitz C. Rutten BP, et al. Among authors: wirths o. Neurobiol Dis. 2003 Mar;12(2):110-20. doi: 10.1016/s0969-9961(02)00015-3. Neurobiol Dis. 2003. PMID: 12667466

9

Hippocampal neuron loss exceeds amyloid plaque load in a transgenic mouse model of Alzheimer's disease.

Schmitz C, Rutten BP, Pielen A, Schäfer S, Wirths O, Tremp G, Czech C, Blanchard V, Multhaup G, Rezaie P, Korr H, Steinbusch HW, Pradier L, Bayer TA. Schmitz C, et al. Among authors: wirths o. Am J Pathol. 2004 Apr;164(4):1495-502. doi: 10.1016/S0002-9440(10)63235-X. Am J Pathol. 2004. PMID: 15039236 Free PMC article.

10

Massive CA1/2 neuronal loss with intraneuronal and N-terminal truncated Abeta42 accumulation in a novel Alzheimer transgenic model.

Casas C, Sergeant N, Itier JM, Blanchard V, Wirths O, van der Kolk N, Vingtdeux V, van de Steeg E, Ret G, Canton T, Drobecq H, Clark A, Bonici B, Delacourte A, Benavides J, Schmitz C, Tremp G, Bayer TA, Benoit P, Pradier L. Casas C, et al. Among authors: wirths o. Am J Pathol. 2004 Oct;165(4):1289-300. doi: 10.1016/s0002-9440(10)63388-3. Am J Pathol. 2004. PMID: 15466394 Free PMC article.

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