Pickard RT - Search Results

1

Discovery, development, and clinical proof of mechanism of LY3463251, a long-acting GDF15 receptor agonist.

Benichou O, Coskun T, Gonciarz MD, Garhyan P, Adams AC, Du Y, Dunbar JD, Martin JA, Mather KJ, Pickard RT, Reynolds VL, Robins DA, Zvada SP, Emmerson PJ. Benichou O, et al. Among authors: pickard rt. Cell Metab. 2023 Feb 7;35(2):274-286.e10. doi: 10.1016/j.cmet.2022.12.011. Epub 2023 Jan 10. Cell Metab. 2023. PMID: 36630958 Free article.

2

The metabolic effects of GDF15 are mediated by the orphan receptor GFRAL.

Emmerson PJ, Wang F, Du Y, Liu Q, Pickard RT, Gonciarz MD, Coskun T, Hamang MJ, Sindelar DK, Ballman KK, Foltz LA, Muppidi A, Alsina-Fernandez J, Barnard GC, Tang JX, Liu X, Mao X, Siegel R, Sloan JH, Mitchell PJ, Zhang BB, Gimeno RE, Shan B, Wu X. Emmerson PJ, et al. Among authors: pickard rt. Nat Med. 2017 Oct;23(10):1215-1219. doi: 10.1038/nm.4393. Epub 2017 Aug 28. Nat Med. 2017. PMID: 28846098

3

Proteolytic cleavage of antigen extends the durability of an anti-PCSK9 monoclonal antibody.

Schroeder KM, Beyer TP, Hansen RJ, Han B, Pickard RT, Wroblewski VJ, Kowala MC, Eacho PI. Schroeder KM, et al. Among authors: pickard rt. J Lipid Res. 2015 Nov;56(11):2124-32. doi: 10.1194/jlr.M061903. Epub 2015 Sep 20. J Lipid Res. 2015. PMID: 26392590 Free PMC article.

4

Serum PCSK9 is associated with multiple metabolic factors in a large Han Chinese population.

Cui Q, Ju X, Yang T, Zhang M, Tang W, Chen Q, Hu Y, Haas JV, Troutt JS, Pickard RT, Darling R, Konrad RJ, Zhou H, Cao G. Cui Q, et al. Among authors: pickard rt. Atherosclerosis. 2010 Dec;213(2):632-6. doi: 10.1016/j.atherosclerosis.2010.09.027. Epub 2010 Oct 30. Atherosclerosis. 2010. PMID: 21040917

5

Synthesis and SAR of novel histamine H3 receptor antagonists.

Jesudason CD, Beavers LS, Cramer JW, Dill J, Finley DR, Lindsley CW, Stevens FC, Gadski RA, Oldham SW, Pickard RT, Siedem CS, Sindelar DK, Singh A, Watson BM, Hipskind PA. Jesudason CD, et al. Among authors: pickard rt. Bioorg Med Chem Lett. 2006 Jul 1;16(13):3415-8. doi: 10.1016/j.bmcl.2006.04.004. Epub 2006 May 3. Bioorg Med Chem Lett. 2006. PMID: 16677814

6

Central H3R activation by thioperamide does not affect energy balance.

Sindelar DK, Shepperd ML, Pickard RT, Alexander-Chacko J, Dill MJ, Cramer JW, Smith DP, Gadski R. Sindelar DK, et al. Among authors: pickard rt. Pharmacol Biochem Behav. 2004 Jun;78(2):275-83. doi: 10.1016/j.pbb.2004.03.019. Pharmacol Biochem Behav. 2004. PMID: 15219768

7

Estrogen receptor-mediated repression of human hepatic lipase gene transcription.

Jones DR, Schmidt RJ, Pickard RT, Foxworthy PS, Eacho PI. Jones DR, et al. Among authors: pickard rt. J Lipid Res. 2002 Mar;43(3):383-91. J Lipid Res. 2002. PMID: 11893774 Free article.

8

Imidazoline receptor antisera-selected (IRAS) cDNA: cloning and characterization.

Piletz JE, Ivanov TR, Sharp JD, Ernsberger P, Chang CH, Pickard RT, Gold G, Roth B, Zhu H, Jones JC, Baldwin J, Reis DJ. Piletz JE, et al. Among authors: pickard rt. DNA Cell Biol. 2000 Jun;19(6):319-29. doi: 10.1089/10445490050043290. DNA Cell Biol. 2000. PMID: 10882231

9

Binding of the imidazoline ligand 3H-2-benzofuranyl-2-imidazoline (BFI) to human brain and platelets. Potentiation by tranylcypromine and role of MAO isoforms.

Steinberg MI, Wiest SA, Pickard RT, Chen K, Shih JC. Steinberg MI, et al. Among authors: pickard rt. Ann N Y Acad Sci. 1999 Jun 21;881:193-8. doi: 10.1111/j.1749-6632.1999.tb09359.x. Ann N Y Acad Sci. 1999. PMID: 10415915 No abstract available.

10

Molecular cloning of two new human paralogs of 85-kDa cytosolic phospholipase A2.

Pickard RT, Strifler BA, Kramer RM, Sharp JD. Pickard RT, et al. J Biol Chem. 1999 Mar 26;274(13):8823-31. doi: 10.1074/jbc.274.13.8823. J Biol Chem. 1999. PMID: 10085124 Free article.

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