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Artesunate versus quinine in the treatment of severe falciparum malaria in African children (AQUAMAT): an open-label, randomised trial.
Dondorp AM, Fanello CI, Hendriksen IC, Gomes E, Seni A, Chhaganlal KD, Bojang K, Olaosebikan R, Anunobi N, Maitland K, Kivaya E, Agbenyega T, Nguah SB, Evans J, Gesase S, Kahabuka C, Mtove G, Nadjm B, Deen J, Mwanga-Amumpaire J, Nansumba M, Karema C, Umulisa N, Uwimana A, Mokuolu OA, Adedoyin OT, Johnson WB, Tshefu AK, Onyamboko MA, Sakulthaew T, Ngum WP, Silamut K, Stepniewska K, Woodrow CJ, Bethell D, Wills B, Oneko M, Peto TE, von Seidlein L, Day NP, White NJ; AQUAMAT group. Dondorp AM, et al. Among authors: karema c. Lancet. 2010 Nov 13;376(9753):1647-57. doi: 10.1016/S0140-6736(10)61924-1. Epub 2010 Nov 7. Lancet. 2010. PMID: 21062666 Free PMC article. Clinical Trial.
A Worldwide Map of Plasmodium falciparum K13-Propeller Polymorphisms.
Ménard D, Khim N, Beghain J, Adegnika AA, Shafiul-Alam M, Amodu O, Rahim-Awab G, Barnadas C, Berry A, Boum Y, Bustos MD, Cao J, Chen JH, Collet L, Cui L, Thakur GD, Dieye A, Djallé D, Dorkenoo MA, Eboumbou-Moukoko CE, Espino FE, Fandeur T, Ferreira-da-Cruz MF, Fola AA, Fuehrer HP, Hassan AM, Herrera S, Hongvanthong B, Houzé S, Ibrahim ML, Jahirul-Karim M, Jiang L, Kano S, Ali-Khan W, Khanthavong M, Kremsner PG, Lacerda M, Leang R, Leelawong M, Li M, Lin K, Mazarati JB, Ménard S, Morlais I, Muhindo-Mavoko H, Musset L, Na-Bangchang K, Nambozi M, Niaré K, Noedl H, Ouédraogo JB, Pillai DR, Pradines B, Quang-Phuc B, Ramharter M, Randrianarivelojosia M, Sattabongkot J, Sheikh-Omar A, Silué KD, Sirima SB, Sutherland C, Syafruddin D, Tahar R, Tang LH, Touré OA, Tshibangu-wa-Tshibangu P, Vigan-Womas I, Warsame M, Wini L, Zakeri S, Kim S, Eam R, Berne L, Khean C, Chy S, Ken M, Loch K, Canier L, Duru V, Legrand E, Barale JC, Stokes B, Straimer J, Witkowski B, Fidock DA, Rogier C, Ringwald P, Ariey F, Mercereau-Puijalon O; KARMA Consortium. Ménard D, et al. N Engl J Med. 2016 Jun 23;374(25):2453-64. doi: 10.1056/NEJMoa1513137. N Engl J Med. 2016. PMID: 27332904 Free PMC article.
Examining the Early Distribution of the Artemisinin-Resistant Plasmodium falciparum kelch13 R561H Mutation in Areas of Higher Transmission in Rwanda.
Kirby R, Giesbrecht D, Karema C, Watson O, Lewis S, Munyaneza T, Butera JD, Juliano JJ, Bailey JA, Mazarati JB. Kirby R, et al. Among authors: karema c. Open Forum Infect Dis. 2023 Mar 21;10(4):ofad149. doi: 10.1093/ofid/ofad149. eCollection 2023 Apr. Open Forum Infect Dis. 2023. PMID: 37096145 Free PMC article.
Prevalence of Falciparum and non-Falciparum Malaria in the 2014-15 Rwanda Demographic Health Survey.
Gaither C, Morgan C, Kirby R, Karema C, Gashema P, White SJ, Topazian HM, Geibrecht D, Thwai K, Boyter K, Munyaneza T, Muvunyi CM, De Dieu Butera J, Bailey JA, Mazarati JB, Juliano JJ. Gaither C, et al. Among authors: karema c. medRxiv [Preprint]. 2024 Jan 10:2024.01.09.24301054. doi: 10.1101/2024.01.09.24301054. medRxiv. 2024. PMID: 38260604 Free PMC article. Preprint.
Expansion of Artemisinin Partial Resistance Mutations and Lack of Histidine Rich Protein-2 and -3 Deletions in Plasmodium falciparum infections from Rukara, Rwanda.
Schreidah C, Giesbrecht D, Gashema P, Young N, Munyaneza T, Muvunyi CM, Thwai K, Mazarati JB, Bailey J, Juliano JJ, Karema C. Schreidah C, et al. Among authors: karema c. medRxiv [Preprint]. 2023 Dec 18:2023.12.17.23300081. doi: 10.1101/2023.12.17.23300081. medRxiv. 2023. PMID: 38196592 Free PMC article. Updated. Preprint.
High frequency of artemisinin partial resistance mutations in the great lake region revealed through rapid pooled deep sequencing.
Young NW, Gashema P, Giesbrecht D, Munyaneza T, Maisha F, Mwebembezi F, Budodo R, Leonetti A, Crudale R, Iradukunda V, Bosco NJ, Boyce RM, Mandara CI, Kanyankole GK, Mulogo E, Ishengoma DS, Hangi S, Karema C, Mazarati JB, Juliano JJ, Bailey JA. Young NW, et al. Among authors: karema c. medRxiv [Preprint]. 2024 May 1:2024.04.29.24306442. doi: 10.1101/2024.04.29.24306442. medRxiv. 2024. PMID: 38746440 Free PMC article. Preprint.
Making the most of malaria chemoprevention.
Littmann J, Achu D, Laufer MK, Karema C, Schellenberg D. Littmann J, et al. Among authors: karema c. Malar J. 2024 Feb 19;23(1):51. doi: 10.1186/s12936-024-04867-5. Malar J. 2024. PMID: 38369497 Free PMC article. Review.
122 results