Wirka RC - Search Results

1

A common connexin-40 gene promoter variant affects connexin-40 expression in human atria and is associated with atrial fibrillation.

Wirka RC, Gore S, Van Wagoner DR, Arking DE, Lubitz SA, Lunetta KL, Benjamin EJ, Alonso A, Ellinor PT, Barnard J, Chung MK, Smith JD. Wirka RC, et al. Circ Arrhythm Electrophysiol. 2011 Feb;4(1):87-93. doi: 10.1161/CIRCEP.110.959726. Epub 2010 Nov 13. Circ Arrhythm Electrophysiol. 2011. PMID: 21076161 Free PMC article.

2

Low prevalence of connexin-40 gene variants in atrial tissues and blood from atrial fibrillation subjects.

Tchou GD, Wirka RC, Van Wagoner DR, Barnard J, Chung MK, Smith JD. Tchou GD, et al. Among authors: wirka rc. BMC Med Genet. 2012 Nov 7;13:102. doi: 10.1186/1471-2350-13-102. BMC Med Genet. 2012. PMID: 23134779 Free PMC article.

3

Coronary Disease-Associated Gene TCF21 Inhibits Smooth Muscle Cell Differentiation by Blocking the Myocardin-Serum Response Factor Pathway.

Nagao M, Lyu Q, Zhao Q, Wirka RC, Bagga J, Nguyen T, Cheng P, Kim JB, Pjanic M, Miano JM, Quertermous T. Nagao M, et al. Among authors: wirka rc. Circ Res. 2020 Feb 14;126(4):517-529. doi: 10.1161/CIRCRESAHA.119.315968. Epub 2019 Dec 9. Circ Res. 2020. PMID: 31815603 Free PMC article.

4

Association of VEGF and VEGFR2 single nucleotide polymorphisms with hypertension and clinical outcome in metastatic clear cell renal cell carcinoma patients treated with sunitinib.

Kim JJ, Vaziri SA, Rini BI, Elson P, Garcia JA, Wirka R, Dreicer R, Ganapathi MK, Ganapathi R. Kim JJ, et al. Cancer. 2012 Apr 1;118(7):1946-54. doi: 10.1002/cncr.26491. Epub 2011 Aug 31. Cancer. 2012. PMID: 21882181 Free PMC article.

5

Advances in Transcriptomics: Investigating Cardiovascular Disease at Unprecedented Resolution.

Wirka RC, Pjanic M, Quertermous T. Wirka RC, et al. Circ Res. 2018 Apr 27;122(9):1200-1220. doi: 10.1161/CIRCRESAHA.117.310910. Circ Res. 2018. PMID: 29700068 Free PMC article. Review.

6

Atheroprotective roles of smooth muscle cell phenotypic modulation and the TCF21 disease gene as revealed by single-cell analysis.

Wirka RC, Wagh D, Paik DT, Pjanic M, Nguyen T, Miller CL, Kundu R, Nagao M, Coller J, Koyano TK, Fong R, Woo YJ, Liu B, Montgomery SB, Wu JC, Zhu K, Chang R, Alamprese M, Tallquist MD, Kim JB, Quertermous T. Wirka RC, et al. Nat Med. 2019 Aug;25(8):1280-1289. doi: 10.1038/s41591-019-0512-5. Epub 2019 Jul 29. Nat Med. 2019. PMID: 31359001 Free PMC article.

7

ZEB2 Shapes the Epigenetic Landscape of Atherosclerosis.

Cheng P, Wirka RC, Shoa Clarke L, Zhao Q, Kundu R, Nguyen T, Nair S, Sharma D, Kim HJ, Shi H, Assimes T, Brian Kim J, Kundaje A, Quertermous T. Cheng P, et al. Among authors: wirka rc. Circulation. 2022 Feb 8;145(6):469-485. doi: 10.1161/CIRCULATIONAHA.121.057789. Epub 2022 Jan 6. Circulation. 2022. PMID: 34990206 Free PMC article.

8

Coronary artery disease genes SMAD3 and TCF21 promote opposing interactive genetic programs that regulate smooth muscle cell differentiation and disease risk.

Iyer D, Zhao Q, Wirka R, Naravane A, Nguyen T, Liu B, Nagao M, Cheng P, Miller CL, Kim JB, Pjanic M, Quertermous T. Iyer D, et al. PLoS Genet. 2018 Oct 11;14(10):e1007681. doi: 10.1371/journal.pgen.1007681. eCollection 2018 Oct. PLoS Genet. 2018. PMID: 30307970 Free PMC article.

9

TCF21 and AP-1 interact through epigenetic modifications to regulate coronary artery disease gene expression.

Zhao Q, Wirka R, Nguyen T, Nagao M, Cheng P, Miller CL, Kim JB, Pjanic M, Quertermous T. Zhao Q, et al. Genome Med. 2019 May 2;11(1):23. doi: 10.1186/s13073-019-0635-9. Genome Med. 2019. PMID: 31014396 Free PMC article.

10

Environment-Sensing Aryl Hydrocarbon Receptor Inhibits the Chondrogenic Fate of Modulated Smooth Muscle Cells in Atherosclerotic Lesions.

Kim JB, Zhao Q, Nguyen T, Pjanic M, Cheng P, Wirka R, Travisano S, Nagao M, Kundu R, Quertermous T. Kim JB, et al. Circulation. 2020 Aug 11;142(6):575-590. doi: 10.1161/CIRCULATIONAHA.120.045981. Epub 2020 May 22. Circulation. 2020. PMID: 32441123 Free PMC article.

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