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Systems analysis of a RIG-I agonist inducing broad spectrum inhibition of virus infectivity.
Goulet ML, Olagnier D, Xu Z, Paz S, Belgnaoui SM, Lafferty EI, Janelle V, Arguello M, Paquet M, Ghneim K, Richards S, Smith A, Wilkinson P, Cameron M, Kalinke U, Qureshi S, Lamarre A, Haddad EK, Sekaly RP, Peri S, Balachandran S, Lin R, Hiscott J. Goulet ML, et al. Among authors: sekaly rp. PLoS Pathog. 2013;9(4):e1003298. doi: 10.1371/journal.ppat.1003298. Epub 2013 Apr 25. PLoS Pathog. 2013. PMID: 23633948 Free PMC article.
Convergence of TCR and cytokine signaling leads to FOXO3a phosphorylation and drives the survival of CD4+ central memory T cells.
Riou C, Yassine-Diab B, Van grevenynghe J, Somogyi R, Greller LD, Gagnon D, Gimmig S, Wilkinson P, Shi Y, Cameron MJ, Campos-Gonzalez R, Balderas RS, Kelvin D, Sekaly RP, Haddad EK. Riou C, et al. Among authors: sekaly rp. J Exp Med. 2007 Jan 22;204(1):79-91. doi: 10.1084/jem.20061681. Epub 2006 Dec 26. J Exp Med. 2007. PMID: 17190839 Free PMC article.
Transcription factor FOXO3a controls the persistence of memory CD4(+) T cells during HIV infection.
van Grevenynghe J, Procopio FA, He Z, Chomont N, Riou C, Zhang Y, Gimmig S, Boucher G, Wilkinson P, Shi Y, Yassine-Diab B, Said EA, Trautmann L, El Far M, Balderas RS, Boulassel MR, Routy JP, Haddad EK, Sekaly RP. van Grevenynghe J, et al. Among authors: sekaly rp. Nat Med. 2008 Mar;14(3):266-74. doi: 10.1038/nm1728. Epub 2008 Mar 2. Nat Med. 2008. PMID: 18311149
Reduced Chronic Lymphocyte Activation following Interferon Alpha Blockade during the Acute Phase of Simian Immunodeficiency Virus Infection in Rhesus Macaques.
Carnathan D, Lawson B, Yu J, Patel K, Billingsley JM, Tharp GK, Delmas OM, Dawoud R, Wilkinson P, Nicolette C, Cameron MJ, Sekaly RP, Bosinger SE, Silvestri G, Vanderford TH. Carnathan D, et al. Among authors: sekaly rp. J Virol. 2018 Apr 13;92(9):e01760-17. doi: 10.1128/JVI.01760-17. Print 2018 May 1. J Virol. 2018. PMID: 29467313 Free PMC article.
Longitudinal assessment of changes in HIV-specific effector activity in HIV-infected patients starting highly active antiretroviral therapy in primary infection.
Alter G, Hatzakis G, Tsoukas CM, Pelley K, Rouleau D, LeBlanc R, Baril JG, Dion H, Lefebvre E, Thomas R, Côté P, Lapointe N, Routy JP, Sékaly RP, Conway B, Bernard NF. Alter G, et al. Among authors: sekaly rp. J Immunol. 2003 Jul 1;171(1):477-88. doi: 10.4049/jimmunol.171.1.477. J Immunol. 2003. PMID: 12817033
CD160 and PD-1 co-expression on HIV-specific CD8 T cells defines a subset with advanced dysfunction.
Peretz Y, He Z, Shi Y, Yassine-Diab B, Goulet JP, Bordi R, Filali-Mouhim A, Loubert JB, El-Far M, Dupuy FP, Boulassel MR, Tremblay C, Routy JP, Bernard N, Balderas R, Haddad EK, Sékaly RP. Peretz Y, et al. Among authors: sekaly rp. PLoS Pathog. 2012;8(8):e1002840. doi: 10.1371/journal.ppat.1002840. Epub 2012 Aug 16. PLoS Pathog. 2012. PMID: 22916009 Free PMC article. Clinical Trial.
Emergence of individual HIV-specific CD8 T cell responses during primary HIV-1 infection can determine long-term disease outcome.
Streeck H, Lu R, Beckwith N, Milazzo M, Liu M, Routy JP, Little S, Jessen H, Kelleher AD, Hecht F, Sekaly RP, Alter G, Heckerman D, Carrington M, Rosenberg ES, Altfeld M. Streeck H, et al. Among authors: sekaly rp. J Virol. 2014 Nov;88(21):12793-801. doi: 10.1128/JVI.02016-14. Epub 2014 Aug 27. J Virol. 2014. PMID: 25165102 Free PMC article.
383 results