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Genome-wide association study of blood pressure extremes identifies variant near UMOD associated with hypertension.
Padmanabhan S, Melander O, Johnson T, Di Blasio AM, Lee WK, Gentilini D, Hastie CE, Menni C, Monti MC, Delles C, Laing S, Corso B, Navis G, Kwakernaak AJ, van der Harst P, Bochud M, Maillard M, Burnier M, Hedner T, Kjeldsen S, Wahlstrand B, Sjögren M, Fava C, Montagnana M, Danese E, Torffvit O, Hedblad B, Snieder H, Connell JM, Brown M, Samani NJ, Farrall M, Cesana G, Mancia G, Signorini S, Grassi G, Eyheramendy S, Wichmann HE, Laan M, Strachan DP, Sever P, Shields DC, Stanton A, Vollenweider P, Teumer A, Völzke H, Rettig R, Newton-Cheh C, Arora P, Zhang F, Soranzo N, Spector TD, Lucas G, Kathiresan S, Siscovick DS, Luan J, Loos RJ, Wareham NJ, Penninx BW, Nolte IM, McBride M, Miller WH, Nicklin SA, Baker AH, Graham D, McDonald RA, Pell JP, Sattar N, Welsh P; Global BPgen Consortium; Munroe P, Caulfield MJ, Zanchetti A, Dominiczak AF. Padmanabhan S, et al. Among authors: van der harst p. PLoS Genet. 2010 Oct 28;6(10):e1001177. doi: 10.1371/journal.pgen.1001177. PLoS Genet. 2010. PMID: 21082022 Free PMC article.
Biological ageing and cardiovascular disease.
Samani NJ, van der Harst P. Samani NJ, et al. Among authors: van der harst p. Heart. 2008 May;94(5):537-9. doi: 10.1136/hrt.2007.136010. Heart. 2008. PMID: 18411343 No abstract available.
Expanding the concept of telomere dysfunction in cardiovascular disease.
van der Harst P, van Veldhuisen DJ, Samani NJ. van der Harst P, et al. Among authors: van veldhuisen dj. Arterioscler Thromb Vasc Biol. 2008 May;28(5):807-8. doi: 10.1161/ATVBAHA.108.164434. Arterioscler Thromb Vasc Biol. 2008. PMID: 18421006 No abstract available.
Telomere biology in heart failure.
Wong LS, de Boer RA, Samani NJ, van Veldhuisen DJ, van der Harst P. Wong LS, et al. Among authors: van der harst p, van veldhuisen dj. Eur J Heart Fail. 2008 Nov;10(11):1049-56. doi: 10.1016/j.ejheart.2008.08.007. Epub 2008 Sep 24. Eur J Heart Fail. 2008. PMID: 18815070 Free article. Review.
Genome-wide haplotype association study identifies the SLC22A3-LPAL2-LPA gene cluster as a risk locus for coronary artery disease.
Trégouët DA, König IR, Erdmann J, Munteanu A, Braund PS, Hall AS, Grosshennig A, Linsel-Nitschke P, Perret C, DeSuremain M, Meitinger T, Wright BJ, Preuss M, Balmforth AJ, Ball SG, Meisinger C, Germain C, Evans A, Arveiler D, Luc G, Ruidavets JB, Morrison C, van der Harst P, Schreiber S, Neureuther K, Schäfer A, Bugert P, El Mokhtari NE, Schrezenmeir J, Stark K, Rubin D, Wichmann HE, Hengstenberg C, Ouwehand W; Wellcome Trust Case Control Consortium; Cardiogenics Consortium; Ziegler A, Tiret L, Thompson JR, Cambien F, Schunkert H, Samani NJ. Trégouët DA, et al. Among authors: van der harst p. Nat Genet. 2009 Mar;41(3):283-5. doi: 10.1038/ng.314. Epub 2009 Feb 8. Nat Genet. 2009. PMID: 19198611
Genome-wide association study identifies eight loci associated with blood pressure.
Newton-Cheh C, Johnson T, Gateva V, Tobin MD, Bochud M, Coin L, Najjar SS, Zhao JH, Heath SC, Eyheramendy S, Papadakis K, Voight BF, Scott LJ, Zhang F, Farrall M, Tanaka T, Wallace C, Chambers JC, Khaw KT, Nilsson P, van der Harst P, Polidoro S, Grobbee DE, Onland-Moret NC, Bots ML, Wain LV, Elliott KS, Teumer A, Luan J, Lucas G, Kuusisto J, Burton PR, Hadley D, McArdle WL; Wellcome Trust Case Control Consortium; Brown M, Dominiczak A, Newhouse SJ, Samani NJ, Webster J, Zeggini E, Beckmann JS, Bergmann S, Lim N, Song K, Vollenweider P, Waeber G, Waterworth DM, Yuan X, Groop L, Orho-Melander M, Allione A, Di Gregorio A, Guarrera S, Panico S, Ricceri F, Romanazzi V, Sacerdote C, Vineis P, Barroso I, Sandhu MS, Luben RN, Crawford GJ, Jousilahti P, Perola M, Boehnke M, Bonnycastle LL, Collins FS, Jackson AU, Mohlke KL, Stringham HM, Valle TT, Willer CJ, Bergman RN, Morken MA, Döring A, Gieger C, Illig T, Meitinger T, Org E, Pfeufer A, Wichmann HE, Kathiresan S, Marrugat J, O'Donnell CJ, Schwartz SM, Siscovick DS, Subirana I, Freimer NB, Hartikainen AL, McCarthy MI, O'Reilly PF, Peltonen L, Pouta A, de Jong PE, Snieder H, van Gilst WH, Clarke R, Goel A, Hamsten A, Peden J… See abstract for full author list ➔ Newton-Cheh C, et al. Among authors: van gilst wh, van der harst p, van der schouw yt. Nat Genet. 2009 Jun;41(6):666-76. doi: 10.1038/ng.361. Epub 2009 May 10. Nat Genet. 2009. PMID: 19430483 Free PMC article.
Renal dysfunction is associated with shorter telomere length in heart failure.
Wong LS, van der Harst P, de Boer RA, Codd V, Huzen J, Samani NJ, Hillege HL, Voors AA, van Gilst WH, Jaarsma T, van Veldhuisen DJ. Wong LS, et al. Among authors: van gilst wh, van der harst p, van veldhuisen dj. Clin Res Cardiol. 2009 Oct;98(10):629-34. doi: 10.1007/s00392-009-0048-7. Epub 2009 Jul 15. Clin Res Cardiol. 2009. PMID: 19603133 Free PMC article.
CCR5Delta32 genotype is associated with outcome in type 2 diabetes mellitus.
Muntinghe FL, Gross S, Bakker SJ, Landman GW, van der Harst P, Bilo HJ, Navis G, Zuurman MW. Muntinghe FL, et al. Among authors: van der harst p. Diabetes Res Clin Pract. 2009 Nov;86(2):140-5. doi: 10.1016/j.diabres.2009.08.013. Epub 2009 Sep 9. Diabetes Res Clin Pract. 2009. PMID: 19744740
640 results