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Genome-wide association study confirms BST1 and suggests a locus on 12q24 as the risk loci for Parkinson's disease in the European population.
Saad M, Lesage S, Saint-Pierre A, Corvol JC, Zelenika D, Lambert JC, Vidailhet M, Mellick GD, Lohmann E, Durif F, Pollak P, Damier P, Tison F, Silburn PA, Tzourio C, Forlani S, Loriot MA, Giroud M, Helmer C, Portet F, Amouyel P, Lathrop M, Elbaz A, Durr A, Martinez M, Brice A; French Parkinson's Disease Genetics Study Group. Saad M, et al. Among authors: lathrop m. Hum Mol Genet. 2011 Feb 1;20(3):615-27. doi: 10.1093/hmg/ddq497. Epub 2010 Nov 17. Hum Mol Genet. 2011. PMID: 21084426
Single nucleotide polymorphisms in TNFSF15 confer susceptibility to Crohn's disease.
Yamazaki K, McGovern D, Ragoussis J, Paolucci M, Butler H, Jewell D, Cardon L, Takazoe M, Tanaka T, Ichimori T, Saito S, Sekine A, Iida A, Takahashi A, Tsunoda T, Lathrop M, Nakamura Y. Yamazaki K, et al. Among authors: lathrop m. Hum Mol Genet. 2005 Nov 15;14(22):3499-506. doi: 10.1093/hmg/ddi379. Epub 2005 Oct 12. Hum Mol Genet. 2005. PMID: 16221758
Novel Crohn disease locus identified by genome-wide association maps to a gene desert on 5p13.1 and modulates expression of PTGER4.
Libioulle C, Louis E, Hansoul S, Sandor C, Farnir F, Franchimont D, Vermeire S, Dewit O, de Vos M, Dixon A, Demarche B, Gut I, Heath S, Foglio M, Liang L, Laukens D, Mni M, Zelenika D, Van Gossum A, Rutgeerts P, Belaiche J, Lathrop M, Georges M. Libioulle C, et al. Among authors: lathrop m. PLoS Genet. 2007 Apr 20;3(4):e58. doi: 10.1371/journal.pgen.0030058. Epub 2007 Mar 5. PLoS Genet. 2007. PMID: 17447842 Free PMC article.
Evidence for linkage of a new region (11p14) to eczema and allergic diseases.
Guilloud-Bataille M, Bouzigon E, Annesi-Maesano I, Bousquet J, Charpin D, Gormand F, Hochez J, Just J, Lemainque A, Le Moual N, Matran R, Neukirch F, Oryszczyn MP, Paty E, Pin I, Vervloet D, Kauffmann F, Lathrop M, Demenais F, Dizier MH. Guilloud-Bataille M, et al. Among authors: lathrop m. Hum Genet. 2008 Jan;122(6):605-14. doi: 10.1007/s00439-007-0439-7. Epub 2007 Oct 18. Hum Genet. 2008. PMID: 17943316 Free PMC article.
Association analysis indicates that a variant GATA-binding site in the PIK3CB promoter is a Cis-acting expression quantitative trait locus for this gene and attenuates insulin resistance in obese children.
Le Stunff C, Dechartres A, Mariot V, Lotton C, Trainor C, Miraglia Del Giudice E, Meyre D, Bieche I, Laurendeau I, Froguel P, Zelenika D, Fallin D, Lathrop M, Roméo PH, Bougnères P. Le Stunff C, et al. Among authors: lathrop m. Diabetes. 2008 Feb;57(2):494-502. doi: 10.2337/db07-1273. Epub 2007 Oct 31. Diabetes. 2008. PMID: 17977952
A susceptibility locus for lung cancer maps to nicotinic acetylcholine receptor subunit genes on 15q25.
Hung RJ, McKay JD, Gaborieau V, Boffetta P, Hashibe M, Zaridze D, Mukeria A, Szeszenia-Dabrowska N, Lissowska J, Rudnai P, Fabianova E, Mates D, Bencko V, Foretova L, Janout V, Chen C, Goodman G, Field JK, Liloglou T, Xinarianos G, Cassidy A, McLaughlin J, Liu G, Narod S, Krokan HE, Skorpen F, Elvestad MB, Hveem K, Vatten L, Linseisen J, Clavel-Chapelon F, Vineis P, Bueno-de-Mesquita HB, Lund E, Martinez C, Bingham S, Rasmuson T, Hainaut P, Riboli E, Ahrens W, Benhamou S, Lagiou P, Trichopoulos D, Holcátová I, Merletti F, Kjaerheim K, Agudo A, Macfarlane G, Talamini R, Simonato L, Lowry R, Conway DI, Znaor A, Healy C, Zelenika D, Boland A, Delepine M, Foglio M, Lechner D, Matsuda F, Blanche H, Gut I, Heath S, Lathrop M, Brennan P. Hung RJ, et al. Among authors: lathrop m. Nature. 2008 Apr 3;452(7187):633-7. doi: 10.1038/nature06885. Nature. 2008. PMID: 18385738 Free article.
Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease.
Barrett JC, Hansoul S, Nicolae DL, Cho JH, Duerr RH, Rioux JD, Brant SR, Silverberg MS, Taylor KD, Barmada MM, Bitton A, Dassopoulos T, Datta LW, Green T, Griffiths AM, Kistner EO, Murtha MT, Regueiro MD, Rotter JI, Schumm LP, Steinhart AH, Targan SR, Xavier RJ; NIDDK IBD Genetics Consortium; Libioulle C, Sandor C, Lathrop M, Belaiche J, Dewit O, Gut I, Heath S, Laukens D, Mni M, Rutgeerts P, Van Gossum A, Zelenika D, Franchimont D, Hugot JP, de Vos M, Vermeire S, Louis E; Belgian-French IBD Consortium; Wellcome Trust Case Control Consortium; Cardon LR, Anderson CA, Drummond H, Nimmo E, Ahmad T, Prescott NJ, Onnie CM, Fisher SA, Marchini J, Ghori J, Bumpstead S, Gwilliam R, Tremelling M, Deloukas P, Mansfield J, Jewell D, Satsangi J, Mathew CG, Parkes M, Georges M, Daly MJ. Barrett JC, et al. Among authors: lathrop m. Nat Genet. 2008 Aug;40(8):955-62. doi: 10.1038/ng.175. Epub 2008 Jun 29. Nat Genet. 2008. PMID: 18587394 Free PMC article.
658 results