Lagor WR - Search Results

1

Trib1 is a lipid- and myocardial infarction-associated gene that regulates hepatic lipogenesis and VLDL production in mice.

Burkhardt R, Toh SA, Lagor WR, Birkeland A, Levin M, Li X, Robblee M, Fedorov VD, Yamamoto M, Satoh T, Akira S, Kathiresan S, Breslow JL, Rader DJ. Burkhardt R, et al. Among authors: lagor wr. J Clin Invest. 2010 Dec;120(12):4410-4. doi: 10.1172/JCI44213. Epub 2010 Nov 15. J Clin Invest. 2010. PMID: 21084752 Free PMC article.

2

LPA disruption with AAV-CRISPR potently lowers plasma apo(a) in transgenic mouse model: A proof-of-concept study.

Doerfler AM, Park SH, Assini JM, Youssef A, Saxena L, Yaseen AB, De Giorgi M, Chuecos M, Hurley AE, Li A, Marcovina SM, Bao G, Boffa MB, Koschinsky ML, Lagor WR. Doerfler AM, et al. Among authors: lagor wr. Mol Ther Methods Clin Dev. 2022 Oct 13;27:337-351. doi: 10.1016/j.omtm.2022.10.009. eCollection 2022 Dec 8. Mol Ther Methods Clin Dev. 2022. PMID: 36381302 Free PMC article.

3

Overexpression of apolipoprotein F reduces HDL cholesterol levels in vivo.

Lagor WR, Brown RJ, Toh SA, Millar JS, Fuki IV, de la Llera-Moya M, Yuen T, Rothblat G, Billheimer JT, Rader DJ. Lagor WR, et al. Arterioscler Thromb Vasc Biol. 2009 Jan;29(1):40-6. doi: 10.1161/ATVBAHA.108.177105. Epub 2008 Nov 13. Arterioscler Thromb Vasc Biol. 2009. PMID: 19008531 Free PMC article.

4

Impact of combined deficiency of hepatic lipase and endothelial lipase on the metabolism of both high-density lipoproteins and apolipoprotein B-containing lipoproteins.

Brown RJ, Lagor WR, Sankaranaravanan S, Yasuda T, Quertermous T, Rothblat GH, Rader DJ. Brown RJ, et al. Among authors: lagor wr. Circ Res. 2010 Aug 6;107(3):357-64. doi: 10.1161/CIRCRESAHA.110.219188. Epub 2010 Jun 17. Circ Res. 2010. PMID: 20558822 Free PMC article.

5

Phospholipidation of HDL--how much is too much?

Lagor WR, Rader DJ. Lagor WR, et al. Clin Chem. 2011 Jan;57(1):4-6. doi: 10.1373/clinchem.2010.156224. Epub 2010 Nov 15. Clin Chem. 2011. PMID: 21078838 No abstract available.

6

Overexpression of apolipoprotein O does not impact on plasma HDL levels or functionality in human apolipoprotein A-I transgenic mice.

Nijstad N, de Boer JF, Lagor WR, Toelle M, Usher D, Annema W, der Giet Mv, Rader DJ, Tietge UJ. Nijstad N, et al. Among authors: lagor wr. Biochim Biophys Acta. 2011 Apr;1811(4):294-9. doi: 10.1016/j.bbalip.2011.01.008. Epub 2011 Feb 3. Biochim Biophys Acta. 2011. PMID: 21296681

7

The effects of apolipoprotein F deficiency on high density lipoprotein cholesterol metabolism in mice.

Lagor WR, Fields DW, Khetarpal SA, Kumaravel A, Lin W, Weintraub N, Wu K, Hamm-Alvarez SF, Drazul-Schrader D, de la Llera-Moya M, Rothblat GH, Rader DJ. Lagor WR, et al. PLoS One. 2012;7(2):e31616. doi: 10.1371/journal.pone.0031616. Epub 2012 Feb 20. PLoS One. 2012. PMID: 22363685 Free PMC article.

8

Adeno-associated virus serotype 8 gene therapy leads to significant lowering of plasma cholesterol levels in humanized mouse models of homozygous and heterozygous familial hypercholesterolemia.

Kassim SH, Li H, Bell P, Somanathan S, Lagor W, Jacobs F, Billheimer J, Wilson JM, Rader DJ. Kassim SH, et al. Hum Gene Ther. 2013 Jan;24(1):19-26. doi: 10.1089/hum.2012.108. Epub 2012 Nov 14. Hum Gene Ther. 2013. PMID: 22985273 Free PMC article.

9

Adeno-associated viruses as liver-directed gene delivery vehicles: focus on lipoprotein metabolism.

Lagor WR, Johnston JC, Lock M, Vandenberghe LH, Rader DJ. Lagor WR, et al. Methods Mol Biol. 2013;1027:273-307. doi: 10.1007/978-1-60327-369-5_13. Methods Mol Biol. 2013. PMID: 23912992

10

Genetic manipulation of the ApoF/Stat2 locus supports an important role for type I interferon signaling in atherosclerosis.

Lagor WR, Fields DW, Bauer RC, Crawford A, Abt MC, Artis D, Wherry EJ, Rader DJ. Lagor WR, et al. Atherosclerosis. 2014 Mar;233(1):234-41. doi: 10.1016/j.atherosclerosis.2013.12.043. Epub 2014 Jan 10. Atherosclerosis. 2014. PMID: 24529150 Free PMC article.

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