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Page 1
Overexpression of apolipoprotein F reduces HDL cholesterol levels in vivo.
Lagor WR, Brown RJ, Toh SA, Millar JS, Fuki IV, de la Llera-Moya M, Yuen T, Rothblat G, Billheimer JT, Rader DJ. Lagor WR, et al. Among authors: rader dj. Arterioscler Thromb Vasc Biol. 2009 Jan;29(1):40-6. doi: 10.1161/ATVBAHA.108.177105. Epub 2008 Nov 13. Arterioscler Thromb Vasc Biol. 2009. PMID: 19008531 Free PMC article.
Loss-of-function variants in endothelial lipase are a cause of elevated HDL cholesterol in humans.
Edmondson AC, Brown RJ, Kathiresan S, Cupples LA, Demissie S, Manning AK, Jensen MK, Rimm EB, Wang J, Rodrigues A, Bamba V, Khetarpal SA, Wolfe ML, Derohannessian S, Li M, Reilly MP, Aberle J, Evans D, Hegele RA, Rader DJ. Edmondson AC, et al. Among authors: rader dj. J Clin Invest. 2009 Apr;119(4):1042-50. doi: 10.1172/JCI37176. Epub 2009 Mar 16. J Clin Invest. 2009. PMID: 19287092 Free PMC article.
From noncoding variant to phenotype via SORT1 at the 1p13 cholesterol locus.
Musunuru K, Strong A, Frank-Kamenetsky M, Lee NE, Ahfeldt T, Sachs KV, Li X, Li H, Kuperwasser N, Ruda VM, Pirruccello JP, Muchmore B, Prokunina-Olsson L, Hall JL, Schadt EE, Morales CR, Lund-Katz S, Phillips MC, Wong J, Cantley W, Racie T, Ejebe KG, Orho-Melander M, Melander O, Koteliansky V, Fitzgerald K, Krauss RM, Cowan CA, Kathiresan S, Rader DJ. Musunuru K, et al. Among authors: rader dj. Nature. 2010 Aug 5;466(7307):714-9. doi: 10.1038/nature09266. Nature. 2010. PMID: 20686566 Free PMC article.
Phospholipidation of HDL--how much is too much?
Lagor WR, Rader DJ. Lagor WR, et al. Among authors: rader dj. Clin Chem. 2011 Jan;57(1):4-6. doi: 10.1373/clinchem.2010.156224. Epub 2010 Nov 15. Clin Chem. 2011. PMID: 21078838 No abstract available.
945 results