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Regulation of AMPA receptor trafficking by secreted protein factors.
Rennich BJ, Luth ES, Moores S, Juo P. Rennich BJ, et al. Among authors: moores s. Front Cell Neurosci. 2023 Nov 27;17:1271169. doi: 10.3389/fncel.2023.1271169. eCollection 2023. Front Cell Neurosci. 2023. PMID: 38089145 Free PMC article. Review.
Amivantamab, an Epidermal Growth Factor Receptor (EGFR) and Mesenchymal-epithelial Transition Factor (MET) Bispecific Antibody, Designed to Enable Multiple Mechanisms of Action and Broad Clinical Applications.
Cho BC, Simi A, Sabari J, Vijayaraghavan S, Moores S, Spira A. Cho BC, et al. Among authors: moores s. Clin Lung Cancer. 2023 Mar;24(2):89-97. doi: 10.1016/j.cllc.2022.11.004. Epub 2022 Nov 11. Clin Lung Cancer. 2023. PMID: 36481319 Free article. Review.
Loss of SNORA73 reprograms cellular metabolism and protects against steatohepatitis.
Sletten AC, Davidson JW, Yagabasan B, Moores S, Schwaiger-Haber M, Fujiwara H, Gale S, Jiang X, Sidhu R, Gelman SJ, Zhao S, Patti GJ, Ory DS, Schaffer JE. Sletten AC, et al. Among authors: moores s. Nat Commun. 2021 Sep 1;12(1):5214. doi: 10.1038/s41467-021-25457-y. Nat Commun. 2021. PMID: 34471131 Free PMC article.
Effect of Antimicrobial Therapy on Respiratory Hospitalization or Death in Adults With Idiopathic Pulmonary Fibrosis: The CleanUP-IPF Randomized Clinical Trial.
Martinez FJ, Yow E, Flaherty KR, Snyder LD, Durheim MT, Wisniewski SR, Sciurba FC, Raghu G, Brooks MM, Kim DY, Dilling DF, Criner GJ, Kim H, Belloli EA, Nambiar AM, Scholand MB, Anstrom KJ, Noth I; CleanUP-IPF Investigators of the Pulmonary Trials Cooperative. Martinez FJ, et al. JAMA. 2021 May 11;325(18):1841-1851. doi: 10.1001/jama.2021.4956. JAMA. 2021. PMID: 33974018 Free PMC article. Clinical Trial.
Discovery of amivantamab (JNJ-61186372), a bispecific antibody targeting EGFR and MET.
Neijssen J, Cardoso RMF, Chevalier KM, Wiegman L, Valerius T, Anderson GM, Moores SL, Schuurman J, Parren PWHI, Strohl WR, Chiu ML. Neijssen J, et al. Among authors: moores sl. J Biol Chem. 2021 Jan-Jun;296:100641. doi: 10.1016/j.jbc.2021.100641. Epub 2021 Apr 8. J Biol Chem. 2021. PMID: 33839159 Free PMC article.
Amivantamab (JNJ-61186372), an Fc Enhanced EGFR/cMet Bispecific Antibody, Induces Receptor Downmodulation and Antitumor Activity by Monocyte/Macrophage Trogocytosis.
Vijayaraghavan S, Lipfert L, Chevalier K, Bushey BS, Henley B, Lenhart R, Sendecki J, Beqiri M, Millar HJ, Packman K, Lorenzi MV, Laquerre S, Moores SL. Vijayaraghavan S, et al. Among authors: moores sl. Mol Cancer Ther. 2020 Oct;19(10):2044-2056. doi: 10.1158/1535-7163.MCT-20-0071. Epub 2020 Aug 3. Mol Cancer Ther. 2020. PMID: 32747419
2-Hydroxypropyl-β-cyclodextrin is the active component in a triple combination formulation for treatment of Niemann-Pick C1 disease.
Davidson J, Molitor E, Moores S, Gale SE, Subramanian K, Jiang X, Sidhu R, Kell P, Zhang J, Fujiwara H, Davidson C, Helquist P, Melancon BJ, Grigalunas M, Liu G, Salahi F, Wiest O, Xu X, Porter FD, Pipalia NH, Cruz DL, Holson EB, Schaffer JE, Walkley SU, Maxfield FR, Ory DS. Davidson J, et al. Among authors: moores s. Biochim Biophys Acta Mol Cell Biol Lipids. 2019 Oct;1864(10):1545-1561. doi: 10.1016/j.bbalip.2019.04.011. Epub 2019 Apr 30. Biochim Biophys Acta Mol Cell Biol Lipids. 2019. PMID: 31051283 Free PMC article.
56 results