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Integrated genetic and epigenetic analysis identifies haplotype-specific methylation in the FTO type 2 diabetes and obesity susceptibility locus.
Bell CG, Finer S, Lindgren CM, Wilson GA, Rakyan VK, Teschendorff AE, Akan P, Stupka E, Down TA, Prokopenko I, Morison IM, Mill J, Pidsley R; International Type 2 Diabetes 1q Consortium; Deloukas P, Frayling TM, Hattersley AT, McCarthy MI, Beck S, Hitman GA. Bell CG, et al. Among authors: rakyan vk. PLoS One. 2010 Nov 18;5(11):e14040. doi: 10.1371/journal.pone.0014040. PLoS One. 2010. PMID: 21124985 Free PMC article.
From genome to epigenome.
Murrell A, Rakyan VK, Beck S. Murrell A, et al. Among authors: rakyan vk. Hum Mol Genet. 2005 Apr 15;14 Spec No 1:R3-R10. doi: 10.1093/hmg/ddi110. Hum Mol Genet. 2005. PMID: 15809270 Review.
Epigenetic variation and inheritance in mammals.
Rakyan VK, Beck S. Rakyan VK, et al. Curr Opin Genet Dev. 2006 Dec;16(6):573-7. doi: 10.1016/j.gde.2006.09.002. Epub 2006 Sep 26. Curr Opin Genet Dev. 2006. PMID: 17005390 Review.
DNA methylation profiling of human chromosomes 6, 20 and 22.
Eckhardt F, Lewin J, Cortese R, Rakyan VK, Attwood J, Burger M, Burton J, Cox TV, Davies R, Down TA, Haefliger C, Horton R, Howe K, Jackson DK, Kunde J, Koenig C, Liddle J, Niblett D, Otto T, Pettett R, Seemann S, Thompson C, West T, Rogers J, Olek A, Berlin K, Beck S. Eckhardt F, et al. Among authors: rakyan vk. Nat Genet. 2006 Dec;38(12):1378-85. doi: 10.1038/ng1909. Epub 2006 Oct 29. Nat Genet. 2006. PMID: 17072317 Free PMC article.
An integrated resource for genome-wide identification and analysis of human tissue-specific differentially methylated regions (tDMRs).
Rakyan VK, Down TA, Thorne NP, Flicek P, Kulesha E, Gräf S, Tomazou EM, Bäckdahl L, Johnson N, Herberth M, Howe KL, Jackson DK, Miretti MM, Fiegler H, Marioni JC, Birney E, Hubbard TJ, Carter NP, Tavaré S, Beck S. Rakyan VK, et al. Genome Res. 2008 Sep;18(9):1518-29. doi: 10.1101/gr.077479.108. Epub 2008 Jun 24. Genome Res. 2008. PMID: 18577705 Free PMC article.
A Bayesian deconvolution strategy for immunoprecipitation-based DNA methylome analysis.
Down TA, Rakyan VK, Turner DJ, Flicek P, Li H, Kulesha E, Gräf S, Johnson N, Herrero J, Tomazou EM, Thorne NP, Bäckdahl L, Herberth M, Howe KL, Jackson DK, Miretti MM, Marioni JC, Birney E, Hubbard TJ, Durbin R, Tavaré S, Beck S. Down TA, et al. Among authors: rakyan vk. Nat Biotechnol. 2008 Jul;26(7):779-85. doi: 10.1038/nbt1414. Nat Biotechnol. 2008. PMID: 18612301 Free PMC article.
Placenta-specific methylation of the vitamin D 24-hydroxylase gene: implications for feedback autoregulation of active vitamin D levels at the fetomaternal interface.
Novakovic B, Sibson M, Ng HK, Manuelpillai U, Rakyan V, Down T, Beck S, Fournier T, Evain-Brion D, Dimitriadis E, Craig JM, Morley R, Saffery R. Novakovic B, et al. J Biol Chem. 2009 May 29;284(22):14838-48. doi: 10.1074/jbc.M809542200. Epub 2009 Feb 23. J Biol Chem. 2009. PMID: 19237542 Free PMC article.
65 results