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Dynamic mathematical modeling of IL13-induced signaling in Hodgkin and primary mediastinal B-cell lymphoma allows prediction of therapeutic targets.
Raia V, Schilling M, Böhm M, Hahn B, Kowarsch A, Raue A, Sticht C, Bohl S, Saile M, Möller P, Gretz N, Timmer J, Theis F, Lehmann WD, Lichter P, Klingmüller U. Raia V, et al. Among authors: bohl s. Cancer Res. 2011 Feb 1;71(3):693-704. doi: 10.1158/0008-5472.CAN-10-2987. Epub 2010 Dec 2. Cancer Res. 2011. PMID: 21127196
Standardizing experimental protocols.
Schilling M, Pfeifer AC, Bohl S, Klingmüller U. Schilling M, et al. Among authors: bohl s. Curr Opin Biotechnol. 2008 Aug;19(4):354-9. doi: 10.1016/j.copbio.2008.06.007. Epub 2008 Jul 19. Curr Opin Biotechnol. 2008. PMID: 18617004 Review.
Model Based Targeting of IL-6-Induced Inflammatory Responses in Cultured Primary Hepatocytes to Improve Application of the JAK Inhibitor Ruxolitinib.
Sobotta S, Raue A, Huang X, Vanlier J, Jünger A, Bohl S, Albrecht U, Hahnel MJ, Wolf S, Mueller NS, D'Alessandro LA, Mueller-Bohl S, Boehm ME, Lucarelli P, Bonefas S, Damm G, Seehofer D, Lehmann WD, Rose-John S, van der Hoeven F, Gretz N, Theis FJ, Ehlting C, Bode JG, Timmer J, Schilling M, Klingmüller U. Sobotta S, et al. Among authors: bohl s. Front Physiol. 2017 Oct 9;8:775. doi: 10.3389/fphys.2017.00775. eCollection 2017. Front Physiol. 2017. PMID: 29062282 Free PMC article.
Primary mouse hepatocytes for systems biology approaches: a standardized in vitro system for modelling of signal transduction pathways.
Klingmüller U, Bauer A, Bohl S, Nickel PJ, Breitkopf K, Dooley S, Zellmer S, Kern C, Merfort I, Sparna T, Donauer J, Walz G, Geyer M, Kreutz C, Hermes M, Götschel F, Hecht A, Walter D, Egger L, Neubert K, Borner C, Brulport M, Schormann W, Sauer C, Baumann F, Preiss R, MacNelly S, Godoy P, Wiercinska E, Ciuclan L, Edelmann J, Zeilinger K, Heinrich M, Zanger UM, Gebhardt R, Maiwald T, Heinrich R, Timmer J, von Weizsäcker F, Hengstler JG. Klingmüller U, et al. Among authors: bohl s. Syst Biol (Stevenage). 2006 Nov;153(6):433-47. doi: 10.1049/ip-syb:20050067. Syst Biol (Stevenage). 2006. PMID: 17186705
The glucocorticoid receptor controls hepatic dyslipidemia through Hes1.
Lemke U, Krones-Herzig A, Berriel Diaz M, Narvekar P, Ziegler A, Vegiopoulos A, Cato AC, Bohl S, Klingmüller U, Screaton RA, Müller-Decker K, Kersten S, Herzig S. Lemke U, et al. Among authors: bohl s. Cell Metab. 2008 Sep;8(3):212-23. doi: 10.1016/j.cmet.2008.08.001. Cell Metab. 2008. PMID: 18762022 Free article.
57 results