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The PKC inhibitor AEB071 may be a therapeutic option for psoriasis.
Skvara H, Dawid M, Kleyn E, Wolff B, Meingassner JG, Knight H, Dumortier T, Kopp T, Fallahi N, Stary G, Burkhart C, Grenet O, Wagner J, Hijazi Y, Morris RE, McGeown C, Rordorf C, Griffiths CE, Stingl G, Jung T. Skvara H, et al. Among authors: stingl g. J Clin Invest. 2008 Sep;118(9):3151-9. doi: 10.1172/JCI35636. J Clin Invest. 2008. PMID: 18688284 Free PMC article. Clinical Trial.
Efalizumab modulates T cell function both in vivo and in vitro.
Koszik F, Stary G, Selenko-Gebauer N, Stingl G. Koszik F, et al. Among authors: stingl g. J Dermatol Sci. 2010 Dec;60(3):159-66. doi: 10.1016/j.jdermsci.2010.10.003. Epub 2010 Oct 12. J Dermatol Sci. 2010. PMID: 21044829
412 results