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Detection of LP2086 on the cell surface of Neisseria meningitidis and its accessibility in the presence of serogroup B capsular polysaccharide.
McNeil LK, Murphy E, Zhao XJ, Guttmann S, Harris SL, Scott AA, Tan C, Mack M, DaSilva I, Alexander K, Mason K, Jiang HQ, Zhu D, Mininni TL, Zlotnick GW, Hoiseth SK, Jones TR, Pride MW, Jansen KU, Anderson AS. McNeil LK, et al. Among authors: murphy e. Vaccine. 2009 May 26;27(25-26):3417-21. doi: 10.1016/j.vaccine.2009.01.075. Epub 2009 Feb 5. Vaccine. 2009. PMID: 19200847
Sequence diversity of the factor H binding protein vaccine candidate in epidemiologically relevant strains of serogroup B Neisseria meningitidis.
Murphy E, Andrew L, Lee KL, Dilts DA, Nunez L, Fink PS, Ambrose K, Borrow R, Findlow J, Taha MK, Deghmane AE, Kriz P, Musilek M, Kalmusova J, Caugant DA, Alvestad T, Mayer LW, Sacchi CT, Wang X, Martin D, von Gottberg A, du Plessis M, Klugman KP, Anderson AS, Jansen KU, Zlotnick GW, Hoiseth SK. Murphy E, et al. J Infect Dis. 2009 Aug 1;200(3):379-89. doi: 10.1086/600141. J Infect Dis. 2009. PMID: 19534597
Broad vaccine coverage predicted for a bivalent recombinant factor H binding protein based vaccine to prevent serogroup B meningococcal disease.
Jiang HQ, Hoiseth SK, Harris SL, McNeil LK, Zhu D, Tan C, Scott AA, Alexander K, Mason K, Miller L, DaSilva I, Mack M, Zhao XJ, Pride MW, Andrew L, Murphy E, Hagen M, French R, Arora A, Jones TR, Jansen KU, Zlotnick GW, Anderson AS. Jiang HQ, et al. Among authors: murphy e. Vaccine. 2010 Aug 23;28(37):6086-93. doi: 10.1016/j.vaccine.2010.06.083. Epub 2010 Jul 7. Vaccine. 2010. PMID: 20619376
Human antibody responses to the meningococcal factor H binding protein (LP2086) during invasive disease, colonization and carriage.
Ala'aldeen DA, Flint M, Oldfield NJ, Omer SA, McNeil LK, Jiang Q, Murphy E, Giardina PC, Novikova EG, Dodge-Scully IL, Bayliss CD, Turner DP, Neal KR, Hoiseth SK, Jansen KU, Anderson AS. Ala'aldeen DA, et al. Among authors: murphy e. Vaccine. 2010 Nov 10;28(48):7667-75. doi: 10.1016/j.vaccine.2010.09.038. Epub 2010 Sep 25. Vaccine. 2010. PMID: 20875489
Prevalence and genetic diversity of candidate vaccine antigens among invasive Neisseria meningitidis isolates in the United States.
Wang X, Cohn A, Comanducci M, Andrew L, Zhao X, MacNeil JR, Schmink S, Muzzi A, Bambini S, Rappuoli R, Pizza M, Murphy E, Hoiseth SK, Jansen KU, Anderson AS, Harrison LH, Clark TA, Messonnier NE, Mayer LW. Wang X, et al. Among authors: murphy e. Vaccine. 2011 Jun 24;29(29-30):4739-44. doi: 10.1016/j.vaccine.2011.04.092. Epub 2011 May 13. Vaccine. 2011. PMID: 21571026
A multi-country evaluation of Neisseria meningitidis serogroup B factor H-binding proteins and implications for vaccine coverage in different age groups.
Hoiseth SK, Murphy E, Andrew L, Vogel U, Frosch M, Hellenbrand W, Abad R, Vazquez JA, Borrow R, Findlow J, Taha MK, Deghmane AE, Caugant DA, Kriz P, Musilek M, Mayer LW, Wang X, Macneil JR, York L, Tan CY, Jansen KU, Anderson AS. Hoiseth SK, et al. Among authors: murphy e. Pediatr Infect Dis J. 2013 Oct;32(10):1096-101. doi: 10.1097/INF.0b013e31829aa63b. Pediatr Infect Dis J. 2013. PMID: 23694830
NMR dynamics and antibody recognition of the meningococcal lipidated outer membrane protein LP2086 in micellar solution.
Mascioni A, Moy FJ, McNeil LK, Murphy E, Bentley BE, Camarda R, Dilts DA, Fink PS, Gusarova V, Hoiseth SK, Malakian K, Mininni T, Novikova E, Lin S, Sigethy S, Zlotnick GW, Tsao DH. Mascioni A, et al. Among authors: murphy e. Biochim Biophys Acta. 2010 Feb;1798(2):87-93. doi: 10.1016/j.bbamem.2009.09.021. Epub 2009 Oct 14. Biochim Biophys Acta. 2010. PMID: 19835839 Free article.
Structural Basis for the Immunogenic Properties of the Meningococcal Vaccine Candidate LP2086.
Mascioni A, Bentley BE, Camarda R, Dilts DA, Fink P, Gusarova V, Hoiseth SK, Jacob J, Lin SL, Malakian K, McNeil LK, Mininni T, Moy F, Murphy E, Novikova E, Sigethy S, Wen Y, Zlotnick GW, Tsao DH. Mascioni A, et al. Among authors: murphy e. J Biol Chem. 2009 Mar 27;284(13):8738-46. doi: 10.1074/jbc.M808831200. Epub 2008 Dec 22. J Biol Chem. 2009. PMID: 19103601 Free PMC article.
3,694 results