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Selective chemical labeling reveals the genome-wide distribution of 5-hydroxymethylcytosine.
Song CX, Szulwach KE, Fu Y, Dai Q, Yi C, Li X, Li Y, Chen CH, Zhang W, Jian X, Wang J, Zhang L, Looney TJ, Zhang B, Godley LA, Hicks LM, Lahn BT, Jin P, He C. Song CX, et al. Among authors: looney tj. Nat Biotechnol. 2011 Jan;29(1):68-72. doi: 10.1038/nbt.1732. Epub 2010 Dec 12. Nat Biotechnol. 2011. PMID: 21151123 Free PMC article.
Hydroxymethylation at gene regulatory regions directs stem/early progenitor cell commitment during erythropoiesis.
Madzo J, Liu H, Rodriguez A, Vasanthakumar A, Sundaravel S, Caces DBD, Looney TJ, Zhang L, Lepore JB, Macrae T, Duszynski R, Shih AH, Song CX, Yu M, Yu Y, Grossman R, Raumann B, Verma A, He C, Levine RL, Lavelle D, Lahn BT, Wickrema A, Godley LA. Madzo J, et al. Among authors: looney tj. Cell Rep. 2014 Jan 16;6(1):231-244. doi: 10.1016/j.celrep.2013.11.044. Epub 2013 Dec 27. Cell Rep. 2014. PMID: 24373966 Free PMC article.
Truncated DNMT3B isoform DNMT3B7 suppresses growth, induces differentiation, and alters DNA methylation in human neuroblastoma.
Ostler KR, Yang Q, Looney TJ, Zhang L, Vasanthakumar A, Tian Y, Kocherginsky M, Raimondi SL, DeMaio JG, Salwen HR, Gu S, Chlenski A, Naranjo A, Gill A, Peddinti R, Lahn BT, Cohn SL, Godley LA. Ostler KR, et al. Among authors: looney tj. Cancer Res. 2012 Sep 15;72(18):4714-23. doi: 10.1158/0008-5472.CAN-12-0886. Epub 2012 Jul 18. Cancer Res. 2012. PMID: 22815530 Free PMC article.
Systematic mapping of occluded genes by cell fusion reveals prevalence and stability of cis-mediated silencing in somatic cells.
Looney TJ, Zhang L, Chen CH, Lee JH, Chari S, Mao FF, Pelizzola M, Zhang L, Lister R, Baker SW, Fernandes CJ, Gaetz J, Foshay KM, Clift KL, Zhang Z, Li WQ, Vallender EJ, Wagner U, Qin JY, Michelini KJ, Bugarija B, Park D, Aryee E, Stricker T, Zhou J, White KP, Ren B, Schroth GP, Ecker JR, Xiang AP, Lahn BT. Looney TJ, et al. Genome Res. 2014 Feb;24(2):267-80. doi: 10.1101/gr.143891.112. Epub 2013 Dec 5. Genome Res. 2014. PMID: 24310002 Free PMC article.
Evidence for a critical role of gene occlusion in cell fate restriction.
Gaetz J, Clift KL, Fernandes CJ, Mao FF, Lee JH, Zhang L, Baker SW, Looney TJ, Foshay KM, Yu WH, Xiang AP, Lahn BT. Gaetz J, et al. Among authors: looney tj. Cell Res. 2012 May;22(5):848-58. doi: 10.1038/cr.2011.190. Epub 2011 Nov 29. Cell Res. 2012. PMID: 22124232 Free PMC article.
Human B-cell isotype switching origins of IgE.
Looney TJ, Lee JY, Roskin KM, Hoh RA, King J, Glanville J, Liu Y, Pham TD, Dekker CL, Davis MM, Boyd SD. Looney TJ, et al. J Allergy Clin Immunol. 2016 Feb;137(2):579-586.e7. doi: 10.1016/j.jaci.2015.07.014. Epub 2015 Aug 22. J Allergy Clin Immunol. 2016. PMID: 26309181 Free PMC article.
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