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A water soluble parthenolide analog suppresses in vivo tumor growth of two tobacco-associated cancers, lung and bladder cancer, by targeting NF-κB and generating reactive oxygen species.
Shanmugam R, Kusumanchi P, Appaiah H, Cheng L, Crooks P, Neelakantan S, Peat T, Klaunig J, Matthews W, Nakshatri H, Sweeney CJ. Shanmugam R, et al. Among authors: cheng l. Int J Cancer. 2011 May 15;128(10):2481-94. doi: 10.1002/ijc.25587. Int J Cancer. 2011. PMID: 20669221 Free PMC article.
Prostate cancer grading, time to go back to the future.
Egevad L, Delahunt B, Bostwick DG, Cheng L, Evans AJ, Gianduzzo T, Graefen M, Hugosson J, Kench JG, Leite KRM, Oxley J, Sauter G, Srigley JR, Stattin P, Tsuzuki T, Yaxley J, Samaratunga H. Egevad L, et al. Among authors: cheng l. BJU Int. 2021 Feb;127(2):165-168. doi: 10.1111/bju.15298. Epub 2020 Nov 27. BJU Int. 2021. PMID: 33206437 Free PMC article. No abstract available.
Restoring chemotherapy and hormone therapy sensitivity by parthenolide in a xenograft hormone refractory prostate cancer model.
Shanmugam R, Jayaprakasan V, Gokmen-Polar Y, Kelich S, Miller KD, Yip-Schneider M, Cheng L, Bhat-Nakshatri P, Sledge GW Jr, Nakshatri H, Zheng QH, Miller MA, DeGrado T, Hutchins GD, Sweeney CJ. Shanmugam R, et al. Among authors: cheng l. Prostate. 2006 Oct 1;66(14):1498-511. doi: 10.1002/pros.20482. Prostate. 2006. PMID: 16921510
Low-grade prostate cancer should still be labelled cancer.
Iczkowski KA, Molina M, Egevad L, Bostwick DG, van Leenders GJLH, La Rosa FG, van der Kwast T, Berney DM, Evans AJ, Wheeler TM, Leite KRM, Samaratunga H, Srigley J, Varma M, Tsuzuki T, Lucia MS, Crawford ED, Harris RG, Stricker P, Lawrentschuk N, Woo HH, Fleshner NE, Shore ND, Yaxley J, Bratt O, Wiklund P, Roberts M, Cheng L, Delahunt B. Iczkowski KA, et al. Among authors: cheng l. BJU Int. 2022 Dec;130(6):741-743. doi: 10.1111/bju.15886. Epub 2022 Sep 20. BJU Int. 2022. PMID: 36083240 No abstract available.
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