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Genetic screens using the piggyBac transposon.
Chew SK, Rad R, Futreal PA, Bradley A, Liu P. Chew SK, et al. Among authors: liu p. Methods. 2011 Apr;53(4):366-71. doi: 10.1016/j.ymeth.2010.12.022. Epub 2010 Dec 23. Methods. 2011. PMID: 21185377 Free PMC article.
PiggyBac transposon mutagenesis: a tool for cancer gene discovery in mice.
Rad R, Rad L, Wang W, Cadinanos J, Vassiliou G, Rice S, Campos LS, Yusa K, Banerjee R, Li MA, de la Rosa J, Strong A, Lu D, Ellis P, Conte N, Yang FT, Liu P, Bradley A. Rad R, et al. Among authors: liu p. Science. 2010 Nov 19;330(6007):1104-7. doi: 10.1126/science.1193004. Epub 2010 Oct 14. Science. 2010. PMID: 20947725 Free PMC article.
PiggyBac Transposon-Based Insertional Mutagenesis in Mice.
Friedrich MJ, Bronner IF, Liu P, Bradley A, Rad R. Friedrich MJ, et al. Among authors: liu p. Methods Mol Biol. 2019;1907:171-183. doi: 10.1007/978-1-4939-8967-6_14. Methods Mol Biol. 2019. PMID: 30543000
PiggyBac transposon tools for recessive screening identify B-cell lymphoma drivers in mice.
Weber J, de la Rosa J, Grove CS, Schick M, Rad L, Baranov O, Strong A, Pfaus A, Friedrich MJ, Engleitner T, Lersch R, Öllinger R, Grau M, Menendez IG, Martella M, Kohlhofer U, Banerjee R, Turchaninova MA, Scherger A, Hoffman GJ, Hess J, Kuhn LB, Ammon T, Kim J, Schneider G, Unger K, Zimber-Strobl U, Heikenwälder M, Schmidt-Supprian M, Yang F, Saur D, Liu P, Steiger K, Chudakov DM, Lenz G, Quintanilla-Martinez L, Keller U, Vassiliou GS, Cadiñanos J, Bradley A, Rad R. Weber J, et al. Among authors: liu p. Nat Commun. 2019 Mar 29;10(1):1415. doi: 10.1038/s41467-019-09180-3. Nat Commun. 2019. PMID: 30926791 Free PMC article.
Chromosomal transposition of PiggyBac in mouse embryonic stem cells.
Wang W, Lin C, Lu D, Ning Z, Cox T, Melvin D, Wang X, Bradley A, Liu P. Wang W, et al. Among authors: liu p. Proc Natl Acad Sci U S A. 2008 Jul 8;105(27):9290-5. doi: 10.1073/pnas.0801017105. Epub 2008 Jun 25. Proc Natl Acad Sci U S A. 2008. PMID: 18579772 Free PMC article.
A conditional piggyBac transposition system for genetic screening in mice identifies oncogenic networks in pancreatic cancer.
Rad R, Rad L, Wang W, Strong A, Ponstingl H, Bronner IF, Mayho M, Steiger K, Weber J, Hieber M, Veltkamp C, Eser S, Geumann U, Öllinger R, Zukowska M, Barenboim M, Maresch R, Cadiñanos J, Friedrich M, Varela I, Constantino-Casas F, Sarver A, Ten Hoeve J, Prosser H, Seidler B, Bauer J, Heikenwälder M, Metzakopian E, Krug A, Ehmer U, Schneider G, Knösel T, Rümmele P, Aust D, Grützmann R, Pilarsky C, Ning Z, Wessels L, Schmid RM, Quail MA, Vassiliou G, Esposito I, Liu P, Saur D, Bradley A. Rad R, et al. Among authors: liu p. Nat Genet. 2015 Jan;47(1):47-56. doi: 10.1038/ng.3164. Epub 2014 Dec 8. Nat Genet. 2015. PMID: 25485836
A DNA transposon-based approach to validate oncogenic mutations in the mouse.
Su Q, Prosser HM, Campos LS, Ortiz M, Nakamura T, Warren M, Dupuy AJ, Jenkins NA, Copeland NG, Bradley A, Liu P. Su Q, et al. Among authors: liu p. Proc Natl Acad Sci U S A. 2008 Dec 16;105(50):19904-9. doi: 10.1073/pnas.0807785105. Epub 2008 Dec 8. Proc Natl Acad Sci U S A. 2008. PMID: 19064922 Free PMC article.
Rapid and efficient reprogramming of somatic cells to induced pluripotent stem cells by retinoic acid receptor gamma and liver receptor homolog 1.
Wang W, Yang J, Liu H, Lu D, Chen X, Zenonos Z, Campos LS, Rad R, Guo G, Zhang S, Bradley A, Liu P. Wang W, et al. Among authors: liu h, liu p. Proc Natl Acad Sci U S A. 2011 Nov 8;108(45):18283-8. doi: 10.1073/pnas.1100893108. Epub 2011 Oct 11. Proc Natl Acad Sci U S A. 2011. PMID: 21990348 Free PMC article.
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