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Triacylglycerol accumulation activates the mitochondrial apoptosis pathway in macrophages.
Aflaki E, Radovic B, Chandak PG, Kolb D, Eisenberg T, Ring J, Fertschai I, Uellen A, Wolinski H, Kohlwein SD, Zechner R, Levak-Frank S, Sattler W, Graier WF, Malli R, Madeo F, Kratky D. Aflaki E, et al. Among authors: levak frank s. J Biol Chem. 2011 Mar 4;286(9):7418-28. doi: 10.1074/jbc.M110.175703. Epub 2011 Jan 1. J Biol Chem. 2011. PMID: 21196579 Free PMC article.
Cholesteryl ester hydrolase activity is abolished in HSL-/- macrophages but unchanged in macrophages lacking KIAA1363.
Buchebner M, Pfeifer T, Rathke N, Chandak PG, Lass A, Schreiber R, Kratzer A, Zimmermann R, Sattler W, Koefeler H, Fröhlich E, Kostner GM, Birner-Gruenberger R, Chiang KP, Haemmerle G, Zechner R, Levak-Frank S, Cravatt B, Kratky D. Buchebner M, et al. J Lipid Res. 2010 Oct;51(10):2896-908. doi: 10.1194/jlr.M004259. Epub 2010 Jul 12. J Lipid Res. 2010. PMID: 20625037 Free PMC article.
Loss of intestinal GATA4 prevents diet-induced obesity and promotes insulin sensitivity in mice.
Patankar JV, Chandak PG, Obrowsky S, Pfeifer T, Diwoky C, Uellen A, Sattler W, Stollberger R, Hoefler G, Heinemann A, Battle M, Duncan S, Kratky D, Levak-Frank S. Patankar JV, et al. Am J Physiol Endocrinol Metab. 2011 Mar;300(3):E478-88. doi: 10.1152/ajpendo.00457.2010. Epub 2010 Dec 21. Am J Physiol Endocrinol Metab. 2011. PMID: 21177287 Free PMC article.
Lack of acyl-CoA:diacylglycerol acyltransferase 1 reduces intestinal cholesterol absorption and attenuates atherosclerosis in apolipoprotein E knockout mice.
Chandak PG, Obrowsky S, Radovic B, Doddapattar P, Aflaki E, Kratzer A, Doshi LS, Povoden S, Ahammer H, Hoefler G, Levak-Frank S, Kratky D. Chandak PG, et al. Among authors: levak frank s. Biochim Biophys Acta. 2011 Dec;1811(12):1011-20. doi: 10.1016/j.bbalip.2011.08.010. Epub 2011 Sep 1. Biochim Biophys Acta. 2011. PMID: 21924378 Free PMC article.
40 results