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Cutting edge: TIGIT has T cell-intrinsic inhibitory functions.
Joller N, Hafler JP, Brynedal B, Kassam N, Spoerl S, Levin SD, Sharpe AH, Kuchroo VK. Joller N, et al. Among authors: levin sd. J Immunol. 2011 Feb 1;186(3):1338-42. doi: 10.4049/jimmunol.1003081. Epub 2011 Jan 3. J Immunol. 2011. PMID: 21199897 Free PMC article.
Requirement for cyclin D3 in lymphocyte development and T cell leukemias.
Sicinska E, Aifantis I, Le Cam L, Swat W, Borowski C, Yu Q, Ferrando AA, Levin SD, Geng Y, von Boehmer H, Sicinski P. Sicinska E, et al. Among authors: levin sd. Cancer Cell. 2003 Dec;4(6):451-61. doi: 10.1016/s1535-6108(03)00301-5. Cancer Cell. 2003. PMID: 14706337 Free article.
Non-Redundant Roles of T Cell Costimulation Pathways in Inflammatory Arthritis Revealed by Dual Blockade of ICOS and CD28 with Acazicolcept (ALPN-101).
Dillon SR, Evans LS, Lewis KE, Debrot S, Blair TC, Mudri S, Kleist K, Levin SD, Bhandari JG, Garrett L, Wolfson MF, Holland PM, Rixon MW, Peng SL. Dillon SR, et al. Among authors: levin sd. Arthritis Rheumatol. 2023 Aug;75(8):1344-1356. doi: 10.1002/art.42484. Epub 2023 May 9. Arthritis Rheumatol. 2023. PMID: 36862144
The engineered CD80 variant fusion therapeutic davoceticept combines checkpoint antagonism with conditional CD28 costimulation for anti-tumor immunity.
Maurer MF, Lewis KE, Kuijper JL, Ardourel D, Gudgeon CJ, Chandrasekaran S, Mudri SL, Kleist KN, Navas C, Wolfson MF, Rixon MW, Swanson R, Dillon SR, Levin SD, Kimbung YR, Akutsu M, Logan DT, Walse B, Swiderek KM, Peng SL. Maurer MF, et al. Among authors: levin sd. Nat Commun. 2022 Apr 4;13(1):1790. doi: 10.1038/s41467-022-29286-5. Nat Commun. 2022. PMID: 35379805 Free PMC article.
ICOSL+ plasmacytoid dendritic cells as inducer of graft-versus-host disease, responsive to a dual ICOS/CD28 antagonist.
Adom D, Dillon SR, Yang J, Liu H, Ramadan A, Kushekhar K, Hund S, Albright A, Kirksey M, Adeniyan T, Lewis KE, Evans L, Wu R, Levin SD, Mudri S, Yang J, Rickel E, Seaberg M, Henderson K, Gudgeon CJ, Wolfson MF, Swanson RM, Swiderek KM, Peng SL, Hippen KL, Blazar BR, Paczesny S. Adom D, et al. Among authors: levin sd. Sci Transl Med. 2020 Oct 7;12(564):eaay4799. doi: 10.1126/scitranslmed.aay4799. Sci Transl Med. 2020. PMID: 33028709 Free PMC article.
72 results