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Therapeutic implications of GIPC1 silencing in cancer.
Chittenden TW, Pak J, Rubio R, Cheng H, Holton K, Prendergast N, Glinskii V, Cai Y, Culhane A, Bentink S, Schwede M, Mar JC, Howe EA, Aryee M, Sultana R, Lanahan AA, Taylor JM, Holmes C, Hahn WC, Zhao JJ, Iglehart JD, Quackenbush J. Chittenden TW, et al. Among authors: iglehart jd. PLoS One. 2010 Dec 30;5(12):e15581. doi: 10.1371/journal.pone.0015581. PLoS One. 2010. PMID: 21209904 Free PMC article.
RelA-Induced Interferon Response Negatively Regulates Proliferation.
Kochupurakkal BS, Wang ZC, Hua T, Culhane AC, Rodig SJ, Rajkovic-Molek K, Lazaro JB, Richardson AL, Biswas DK, Iglehart JD. Kochupurakkal BS, et al. Among authors: iglehart jd. PLoS One. 2015 Oct 13;10(10):e0140243. doi: 10.1371/journal.pone.0140243. eCollection 2015. PLoS One. 2015. PMID: 26460486 Free PMC article.
SIK1 couples LKB1 to p53-dependent anoikis and suppresses metastasis.
Cheng H, Liu P, Wang ZC, Zou L, Santiago S, Garbitt V, Gjoerup OV, Iglehart JD, Miron A, Richardson AL, Hahn WC, Zhao JJ. Cheng H, et al. Among authors: iglehart jd. Sci Signal. 2009 Jul 21;2(80):ra35. doi: 10.1126/scisignal.2000369. Sci Signal. 2009. PMID: 19622832 Free PMC article.
Profiles of genomic instability in high-grade serous ovarian cancer predict treatment outcome.
Wang ZC, Birkbak NJ, Culhane AC, Drapkin R, Fatima A, Tian R, Schwede M, Alsop K, Daniels KE, Piao H, Liu J, Etemadmoghadam D, Miron A, Salvesen HB, Mitchell G, DeFazio A, Quackenbush J, Berkowitz RS, Iglehart JD, Bowtell DD; Australian Ovarian Cancer Study Group; Matulonis UA. Wang ZC, et al. Among authors: iglehart jd. Clin Cancer Res. 2012 Oct 15;18(20):5806-15. doi: 10.1158/1078-0432.CCR-12-0857. Epub 2012 Aug 21. Clin Cancer Res. 2012. PMID: 22912389 Free PMC article.
CDK7-dependent transcriptional addiction in triple-negative breast cancer.
Wang Y, Zhang T, Kwiatkowski N, Abraham BJ, Lee TI, Xie S, Yuzugullu H, Von T, Li H, Lin Z, Stover DG, Lim E, Wang ZC, Iglehart JD, Young RA, Gray NS, Zhao JJ. Wang Y, et al. Among authors: iglehart jd. Cell. 2015 Sep 24;163(1):174-86. doi: 10.1016/j.cell.2015.08.063. Cell. 2015. PMID: 26406377 Free PMC article.
Combination inhibition of PI3K and mTORC1 yields durable remissions in mice bearing orthotopic patient-derived xenografts of HER2-positive breast cancer brain metastases.
Ni J, Ramkissoon SH, Xie S, Goel S, Stover DG, Guo H, Luu V, Marco E, Ramkissoon LA, Kang YJ, Hayashi M, Nguyen QD, Ligon AH, Du R, Claus EB, Alexander BM, Yuan GC, Wang ZC, Iglehart JD, Krop IE, Roberts TM, Winer EP, Lin NU, Ligon KL, Zhao JJ. Ni J, et al. Among authors: iglehart jd. Nat Med. 2016 Jul;22(7):723-6. doi: 10.1038/nm.4120. Epub 2016 Jun 6. Nat Med. 2016. PMID: 27270588 Free PMC article.
150 results