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Loss of subcellular lipid transport due to ARV1 deficiency disrupts organelle homeostasis and activates the unfolded protein response.
Shechtman CF, Henneberry AL, Seimon TA, Tinkelenberg AH, Wilcox LJ, Lee E, Fazlollahi M, Munkacsi AB, Bussemaker HJ, Tabas I, Sturley SL. Shechtman CF, et al. Among authors: seimon ta. J Biol Chem. 2011 Apr 8;286(14):11951-9. doi: 10.1074/jbc.M110.215038. Epub 2011 Jan 25. J Biol Chem. 2011. PMID: 21266578 Free PMC article.
Macrophage apoptosis in advanced atherosclerosis.
Tabas I, Seimon T, Timmins J, Li G, Lim W. Tabas I, et al. Ann N Y Acad Sci. 2009 Sep;1173 Suppl 1(Suppl 1):E40-5. doi: 10.1111/j.1749-6632.2009.04957.x. Ann N Y Acad Sci. 2009. PMID: 19751413 Free PMC article.
Induction of ER stress in macrophages of tuberculosis granulomas.
Seimon TA, Kim MJ, Blumenthal A, Koo J, Ehrt S, Wainwright H, Bekker LG, Kaplan G, Nathan C, Tabas I, Russell DG. Seimon TA, et al. PLoS One. 2010 Sep 15;5(9):e12772. doi: 10.1371/journal.pone.0012772. PLoS One. 2010. PMID: 20856677 Free PMC article.
Free cholesterol accumulation in macrophage membranes activates Toll-like receptors and p38 mitogen-activated protein kinase and induces cathepsin K.
Sun Y, Ishibashi M, Seimon T, Lee M, Sharma SM, Fitzgerald KA, Samokhin AO, Wang Y, Sayers S, Aikawa M, Jerome WG, Ostrowski MC, Bromme D, Libby P, Tabas IA, Welch CL, Tall AR. Sun Y, et al. Circ Res. 2009 Feb 27;104(4):455-65. doi: 10.1161/CIRCRESAHA.108.182568. Epub 2009 Jan 2. Circ Res. 2009. PMID: 19122179 Free PMC article.
Signal transducer and activator of transcription-1 is critical for apoptosis in macrophages subjected to endoplasmic reticulum stress in vitro and in advanced atherosclerotic lesions in vivo.
Lim WS, Timmins JM, Seimon TA, Sadler A, Kolodgie FD, Virmani R, Tabas I. Lim WS, et al. Among authors: seimon ta. Circulation. 2008 Feb 19;117(7):940-51. doi: 10.1161/CIRCULATIONAHA.107.711275. Epub 2008 Jan 28. Circulation. 2008. PMID: 18227389 Free PMC article.
50 results