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Transforming growth factor-beta receptor inhibition enhances adenoviral infectability of carcinoma cells via up-regulation of Coxsackie and Adenovirus Receptor in conjunction with reversal of epithelial-mesenchymal transition.
Lacher MD, Tiirikainen MI, Saunier EF, Christian C, Anders M, Oft M, Balmain A, Akhurst RJ, Korn WM. Lacher MD, et al. Among authors: akhurst rj. Cancer Res. 2006 Feb 1;66(3):1648-57. doi: 10.1158/0008-5472.CAN-05-2328. Cancer Res. 2006. PMID: 16452224
TGF beta inhibition for cancer therapy.
Saunier EF, Akhurst RJ. Saunier EF, et al. Among authors: akhurst rj. Curr Cancer Drug Targets. 2006 Nov;6(7):565-78. doi: 10.2174/156800906778742460. Curr Cancer Drug Targets. 2006. PMID: 17100564 Review.
TGFβ1 inhibition increases the radiosensitivity of breast cancer cells in vitro and promotes tumor control by radiation in vivo.
Bouquet F, Pal A, Pilones KA, Demaria S, Hann B, Akhurst RJ, Babb JS, Lonning SM, DeWyngaert JK, Formenti SC, Barcellos-Hoff MH. Bouquet F, et al. Among authors: akhurst rj. Clin Cancer Res. 2011 Nov 1;17(21):6754-65. doi: 10.1158/1078-0432.CCR-11-0544. Epub 2011 Oct 25. Clin Cancer Res. 2011. PMID: 22028490 Free PMC article.
Mouse and human strategies identify PTPN14 as a modifier of angiogenesis and hereditary haemorrhagic telangiectasia.
Benzinou M, Clermont FF, Letteboer TG, Kim JH, Espejel S, Harradine KA, Arbelaez J, Luu MT, Roy R, Quigley D, Higgins MN, Zaid M, Aouizerat BE, van Amstel JK, Giraud S, Dupuis-Girod S, Lesca G, Plauchu H, Hughes CC, Westermann CJ, Akhurst RJ. Benzinou M, et al. Among authors: akhurst rj. Nat Commun. 2012 Jan 10;3:616. doi: 10.1038/ncomms1633. Nat Commun. 2012. PMID: 22233626 Free PMC article.
129 results