Walden H - Search Results

1

Hydrophobic, aromatic, and electrostatic interactions play a central role in amyloid fibril formation and stability.

Marshall KE, Morris KL, Charlton D, O'Reilly N, Lewis L, Walden H, Serpell LC. Marshall KE, et al. Among authors: walden h. Biochemistry. 2011 Mar 29;50(12):2061-71. doi: 10.1021/bi101936c. Epub 2011 Feb 22. Biochemistry. 2011. PMID: 21288003

2

The structure of the catalytic subunit FANCL of the Fanconi anemia core complex.

Cole AR, Lewis LP, Walden H. Cole AR, et al. Among authors: walden h. Nat Struct Mol Biol. 2010 Mar;17(3):294-8. doi: 10.1038/nsmb.1759. Epub 2010 Feb 14. Nat Struct Mol Biol. 2010. PMID: 20154706 Free PMC article.

3

Structural analysis of human FANCL, the E3 ligase in the Fanconi anemia pathway.

Hodson C, Cole AR, Lewis LP, Miles JA, Purkiss A, Walden H. Hodson C, et al. Among authors: walden h. J Biol Chem. 2011 Sep 16;286(37):32628-37. doi: 10.1074/jbc.M111.244632. Epub 2011 Jul 20. J Biol Chem. 2011. PMID: 21775430 Free PMC article.

4

The Fanconi Anemia DNA Repair Pathway Is Regulated by an Interaction between Ubiquitin and the E2-like Fold Domain of FANCL.

Miles JA, Frost MG, Carroll E, Rowe ML, Howard MJ, Sidhu A, Chaugule VK, Alpi AF, Walden H. Miles JA, et al. Among authors: walden h. J Biol Chem. 2015 Aug 21;290(34):20995-21006. doi: 10.1074/jbc.M115.675835. Epub 2015 Jul 6. J Biol Chem. 2015. PMID: 26149689 Free PMC article.

5

Structure of the human FANCL RING-Ube2T complex reveals determinants of cognate E3-E2 selection.

Hodson C, Purkiss A, Miles JA, Walden H. Hodson C, et al. Among authors: walden h. Structure. 2014 Feb 4;22(2):337-44. doi: 10.1016/j.str.2013.12.004. Epub 2014 Jan 2. Structure. 2014. PMID: 24389026 Free PMC article.

6

Parkin-phosphoubiquitin complex reveals cryptic ubiquitin-binding site required for RBR ligase activity.

Kumar A, Chaugule VK, Condos TEC, Barber KR, Johnson C, Toth R, Sundaramoorthy R, Knebel A, Shaw GS, Walden H. Kumar A, et al. Among authors: walden h. Nat Struct Mol Biol. 2017 May;24(5):475-483. doi: 10.1038/nsmb.3400. Epub 2017 Apr 17. Nat Struct Mol Biol. 2017. PMID: 28414322 Free PMC article.

7

Structural basis of FANCD2 deubiquitination by USP1-UAF1.

Rennie ML, Arkinson C, Chaugule VK, Toth R, Walden H. Rennie ML, et al. Among authors: walden h. Nat Struct Mol Biol. 2021 Apr;28(4):356-364. doi: 10.1038/s41594-021-00576-8. Epub 2021 Apr 1. Nat Struct Mol Biol. 2021. PMID: 33795880 Free article.

8

Towards a molecular understanding of the fanconi anemia core complex.

Hodson C, Walden H. Hodson C, et al. Among authors: walden h. Anemia. 2012;2012:926787. doi: 10.1155/2012/926787. Epub 2012 May 22. Anemia. 2012. PMID: 22675617 Free PMC article.

9

The Fanconi anemia DNA repair pathway: structural and functional insights into a complex disorder.

Walden H, Deans AJ. Walden H, et al. Annu Rev Biophys. 2014;43:257-78. doi: 10.1146/annurev-biophys-051013-022737. Annu Rev Biophys. 2014. PMID: 24773018 Review.

10

Allosteric mechanism for site-specific ubiquitination of FANCD2.

Chaugule VK, Arkinson C, Rennie ML, Kämäräinen O, Toth R, Walden H. Chaugule VK, et al. Among authors: walden h. Nat Chem Biol. 2020 Mar;16(3):291-301. doi: 10.1038/s41589-019-0426-z. Epub 2019 Dec 23. Nat Chem Biol. 2020. PMID: 31873223 Free PMC article.

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