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Disease activity, ANCA, and IL23R genotype status determine early response to infliximab in patients with ulcerative colitis.
Jürgens M, Laubender RP, Hartl F, Weidinger M, Seiderer J, Wagner J, Wetzke M, Beigel F, Pfennig S, Stallhofer J, Schnitzler F, Tillack C, Lohse P, Göke B, Glas J, Ochsenkühn T, Brand S. Jürgens M, et al. Among authors: laubender rp. Am J Gastroenterol. 2010 Aug;105(8):1811-9. doi: 10.1038/ajg.2010.95. Epub 2010 Mar 2. Am J Gastroenterol. 2010. PMID: 20197757
The NOD2 single nucleotide polymorphisms rs2066843 and rs2076756 are novel and common Crohn's disease susceptibility gene variants.
Glas J, Seiderer J, Tillack C, Pfennig S, Beigel F, Jürgens M, Olszak T, Laubender RP, Weidinger M, Müller-Myhsok B, Göke B, Ochsenkühn T, Lohse P, Diegelmann J, Czamara D, Brand S. Glas J, et al. Among authors: laubender rp. PLoS One. 2010 Dec 30;5(12):e14466. doi: 10.1371/journal.pone.0014466. PLoS One. 2010. PMID: 21209938 Free PMC article.
The presence of fistulas and NOD2 homozygosity strongly predict intestinal stenosis in Crohn's disease independent of the IL23R genotype.
Jürgens M, Brand S, Laubender RP, Seiderer J, Glas J, Wetzke M, Wagner J, Pfennig S, Tillack C, Beigel F, Weidinger M, Schnitzler F, Kreis ME, Göke B, Lohse P, Herrmann K, Ochsenkühn T. Jürgens M, et al. Among authors: laubender rp. J Gastroenterol. 2010 Jul;45(7):721-31. doi: 10.1007/s00535-010-0231-7. Epub 2010 Apr 29. J Gastroenterol. 2010. PMID: 20428899
Anti-TNF antibody-induced psoriasiform skin lesions in patients with inflammatory bowel disease are characterised by interferon-γ-expressing Th1 cells and IL-17A/IL-22-expressing Th17 cells and respond to anti-IL-12/IL-23 antibody treatment.
Tillack C, Ehmann LM, Friedrich M, Laubender RP, Papay P, Vogelsang H, Stallhofer J, Beigel F, Bedynek A, Wetzke M, Maier H, Koburger M, Wagner J, Glas J, Diegelmann J, Koglin S, Dombrowski Y, Schauber J, Wollenberg A, Brand S. Tillack C, et al. Among authors: laubender rp. Gut. 2014 Apr;63(4):567-77. doi: 10.1136/gutjnl-2012-302853. Epub 2013 Mar 6. Gut. 2014. PMID: 23468464
Chemerin is associated with markers of inflammation and components of the metabolic syndrome but does not predict coronary atherosclerosis.
Lehrke M, Becker A, Greif M, Stark R, Laubender RP, von Ziegler F, Lebherz C, Tittus J, Reiser M, Becker C, Göke B, Leber AW, Parhofer KG, Broedl UC. Lehrke M, et al. Among authors: laubender rp. Eur J Endocrinol. 2009 Aug;161(2):339-44. doi: 10.1530/EJE-09-0380. Epub 2009 Jun 4. Eur J Endocrinol. 2009. PMID: 19497986
MMP-1 serum levels predict coronary atherosclerosis in humans.
Lehrke M, Greif M, Broedl UC, Lebherz C, Laubender RP, Becker A, von Ziegler F, Tittus J, Reiser M, Becker C, Göke B, Steinbeck G, Leber AW, Parhofer KG. Lehrke M, et al. Among authors: laubender rp. Cardiovasc Diabetol. 2009 Sep 14;8:50. doi: 10.1186/1475-2840-8-50. Cardiovasc Diabetol. 2009. PMID: 19751510 Free PMC article.
97 results