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GIP does not potentiate the antidiabetic effects of GLP-1 in hyperglycemic patients with type 2 diabetes.
Diabetes. 2011 Apr;60(4):1270-6. doi: 10.2337/db10-1332. Epub 2011 Feb 17.
Diabetes. 2011.
PMID: 21330636
Free PMC article.
Clinical Trial.
Inhibition of DPP-4 with vildagliptin improved insulin secretion in response to oral as well as "isoglycemic" intravenous glucose without numerically changing the incretin effect in patients with type 2 diabetes.
Vardarli I, Nauck MA, Köthe LD, Deacon CF, Holst JJ, Schweizer A, Foley JE.
Vardarli I, et al. Among authors: kothe ld.
J Clin Endocrinol Metab. 2011 Apr;96(4):945-54. doi: 10.1210/jc.2010-2178. Epub 2011 Jan 14.
J Clin Endocrinol Metab. 2011.
PMID: 21239518
Clinical Trial.
Item in Clipboard
Quantification of the Contribution of GLP-1 to Mediating Insulinotropic Effects of DPP-4 Inhibition With Vildagliptin in Healthy Subjects and Patients With Type 2 Diabetes Using Exendin [9-39] as a GLP-1 Receptor Antagonist.
Nauck MA, Kind J, Köthe LD, Holst JJ, Deacon CF, Broschag M, He YL, Kjems L, Foley J.
Nauck MA, et al. Among authors: kothe ld.
Diabetes. 2016 Aug;65(8):2440-7. doi: 10.2337/db16-0107. Epub 2016 Apr 5.
Diabetes. 2016.
PMID: 27207543
Clinical Trial.
Item in Clipboard
Glycaemic rises after waking up in response to an alarm clock in type 1-diabetic patients analysed with continuous glucose monitoring (GlucoDay® S).
Berndt-Zipfel C, Köthe L, Nawrodt B, Mraz B, Patzelt-Bath A, Nauck MA.
Berndt-Zipfel C, et al.
Exp Clin Endocrinol Diabetes. 2011 Jan;119(1):56-8. doi: 10.1055/s-0030-1265162. Epub 2011 Jan 18.
Exp Clin Endocrinol Diabetes. 2011.
PMID: 21246465
Clinical Trial.
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