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Schizophrenia susceptibility alleles are enriched for alleles that affect gene expression in adult human brain.
Richards AL, Jones L, Moskvina V, Kirov G, Gejman PV, Levinson DF, Sanders AR; Molecular Genetics of Schizophrenia Collaboration (MGS); International Schizophrenia Consortium (ISC); Purcell S, Visscher PM, Craddock N, Owen MJ, Holmans P, O'Donovan MC. Richards AL, et al. Among authors: holmans p. Mol Psychiatry. 2012 Feb;17(2):193-201. doi: 10.1038/mp.2011.11. Epub 2011 Feb 22. Mol Psychiatry. 2012. PMID: 21339752 Free PMC article.
No major schizophrenia locus detected on chromosome 1q in a large multicenter sample.
Levinson DF, Holmans PA, Laurent C, Riley B, Pulver AE, Gejman PV, Schwab SG, Williams NM, Owen MJ, Wildenauer DB, Sanders AR, Nestadt G, Mowry BJ, Wormley B, Bauché S, Soubigou S, Ribble R, Nertney DA, Liang KY, Martinolich L, Maier W, Norton N, Williams H, Albus M, Carpenter EB, DeMarchi N, Ewen-White KR, Walsh D, Jay M, Deleuze JF, O'Neill FA, Papadimitriou G, Weilbaecher A, Lerer B, O'Donovan MC, Dikeos D, Silverman JM, Kendler KS, Mallet J, Crowe RR, Walters M. Levinson DF, et al. Science. 2002 Apr 26;296(5568):739-41. doi: 10.1126/science.1069914. Science. 2002. PMID: 11976456
Genomewide significant linkage to recurrent, early-onset major depressive disorder on chromosome 15q.
Holmans P, Zubenko GS, Crowe RR, DePaulo JR Jr, Scheftner WA, Weissman MM, Zubenko WN, Boutelle S, Murphy-Eberenz K, MacKinnon D, McInnis MG, Marta DH, Adams P, Knowles JA, Gladis M, Thomas J, Chellis J, Miller E, Levinson DF. Holmans P, et al. Am J Hum Genet. 2004 Jun;74(6):1154-67. doi: 10.1086/421333. Epub 2004 Apr 22. Am J Hum Genet. 2004. PMID: 15108123 Free PMC article.
Genome screen for loci influencing age at onset and rate of decline in late onset Alzheimer's disease.
Holmans P, Hamshere M, Hollingworth P, Rice F, Tunstall N, Jones S, Moore P, Wavrant DeVrieze F, Myers A, Crook R, Compton D, Marshall H, Meyer D, Shears S, Booth J, Ramic D, Williams N, Norton N, Abraham R, Kehoe P, Williams H, Rudrasingham V, O'Donovan M, Jones L, Hardy J, Goate A, Lovestone S, Owen M, Williams J. Holmans P, et al. Am J Med Genet B Neuropsychiatr Genet. 2005 May 5;135B(1):24-32. doi: 10.1002/ajmg.b.30114. Am J Med Genet B Neuropsychiatr Genet. 2005. PMID: 15729734
Genomewide linkage scan in schizoaffective disorder: significant evidence for linkage at 1q42 close to DISC1, and suggestive evidence at 22q11 and 19p13.
Hamshere ML, Bennett P, Williams N, Segurado R, Cardno A, Norton N, Lambert D, Williams H, Kirov G, Corvin A, Holmans P, Jones L, Jones I, Gill M, O'Donovan MC, Owen MJ, Craddock N. Hamshere ML, et al. Among authors: holmans p. Arch Gen Psychiatry. 2005 Oct;62(10):1081-8. doi: 10.1001/archpsyc.62.10.1081. Arch Gen Psychiatry. 2005. PMID: 16203953
Regional and cellular gene expression changes in human Huntington's disease brain.
Hodges A, Strand AD, Aragaki AK, Kuhn A, Sengstag T, Hughes G, Elliston LA, Hartog C, Goldstein DR, Thu D, Hollingsworth ZR, Collin F, Synek B, Holmans PA, Young AB, Wexler NS, Delorenzi M, Kooperberg C, Augood SJ, Faull RL, Olson JM, Jones L, Luthi-Carter R. Hodges A, et al. Hum Mol Genet. 2006 Mar 15;15(6):965-77. doi: 10.1093/hmg/ddl013. Epub 2006 Feb 8. Hum Mol Genet. 2006. PMID: 16467349
440 results