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Post-traumatic stress disorder is associated with PACAP and the PAC1 receptor.
Ressler KJ, Mercer KB, Bradley B, Jovanovic T, Mahan A, Kerley K, Norrholm SD, Kilaru V, Smith AK, Myers AJ, Ramirez M, Engel A, Hammack SE, Toufexis D, Braas KM, Binder EB, May V. Ressler KJ, et al. Among authors: toufexis d. Nature. 2011 Feb 24;470(7335):492-7. doi: 10.1038/nature09856. Nature. 2011. PMID: 21350482 Free PMC article.
Pituitary adenylate cyclase-activating polypeptide (PACAP) in the bed nucleus of the stria terminalis (BNST) increases corticosterone in male and female rats.
Lezak KR, Roelke E, Harris OM, Choi I, Edwards S, Gick N, Cocchiaro G, Missig G, Roman CW, Braas KM, Toufexis DJ, May V, Hammack SE. Lezak KR, et al. Among authors: toufexis dj. Psychoneuroendocrinology. 2014 Jul;45:11-20. doi: 10.1016/j.psyneuen.2014.03.007. Epub 2014 Mar 25. Psychoneuroendocrinology. 2014. PMID: 24845172 Free PMC article.
PACAP in the BNST produces anorexia and weight loss in male and female rats.
Kocho-Schellenberg M, Lezak KR, Harris OM, Roelke E, Gick N, Choi I, Edwards S, Wasserman E, Toufexis DJ, Braas KM, May V, Hammack SE. Kocho-Schellenberg M, et al. Neuropsychopharmacology. 2014 Jun;39(7):1614-23. doi: 10.1038/npp.2014.8. Epub 2014 Jan 17. Neuropsychopharmacology. 2014. PMID: 24434744 Free PMC article.
Continuous expression of corticotropin-releasing factor in the central nucleus of the amygdala emulates the dysregulation of the stress and reproductive axes.
Keen-Rhinehart E, Michopoulos V, Toufexis DJ, Martin EI, Nair H, Ressler KJ, Davis M, Owens MJ, Nemeroff CB, Wilson ME. Keen-Rhinehart E, et al. Among authors: toufexis dj. Mol Psychiatry. 2009 Jan;14(1):37-50. doi: 10.1038/mp.2008.91. Epub 2008 Aug 12. Mol Psychiatry. 2009. PMID: 18698320 Free PMC article.
Stress and the reproductive axis.
Toufexis D, Rivarola MA, Lara H, Viau V. Toufexis D, et al. J Neuroendocrinol. 2014 Sep;26(9):573-86. doi: 10.1111/jne.12179. J Neuroendocrinol. 2014. PMID: 25040027 Free PMC article. Review.
54 results