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Deep sequencing of the Nicastrin gene in pooled DNA, the identification of genetic variants that affect risk of Alzheimer's disease.
Lupton MK, Proitsi P, Danillidou M, Tsolaki M, Hamilton G, Wroe R, Pritchard M, Lord K, Martin BM, Kloszewska I, Soininen H, Mecocci P, Vellas B, Harold D, Hollingworth P, Lovestone S, Powell JF. Lupton MK, et al. Among authors: pritchard m. PLoS One. 2011 Feb 25;6(2):e17298. doi: 10.1371/journal.pone.0017298. PLoS One. 2011. PMID: 21364883 Free PMC article.
Giving dementia a voice.
Callard F, Lovestone S, Pritchard M. Callard F, et al. Among authors: pritchard m. Ment Health Today. 2010 Jul-Aug:34-5. Ment Health Today. 2010. PMID: 20700944 No abstract available.
Alzheimer's disease and age-related macular degeneration have different genetic models for complement gene variation.
Proitsi P, Lupton MK, Dudbridge F, Tsolaki M, Hamilton G, Daniilidou M, Pritchard M, Lord K, Martin BM, Johnson J, Craig D, Todd S, McGuinness B, Hollingworth P, Harold D, Kloszewska I, Soininen H, Mecocci P, Velas B, Gill M, Lawlor B, Rubinsztein DC, Brayne C, Passmore PA, Williams J, Lovestone S, Powell JF. Proitsi P, et al. Among authors: pritchard m. Neurobiol Aging. 2012 Aug;33(8):1843.e9-17. doi: 10.1016/j.neurobiolaging.2011.12.036. Epub 2012 Feb 1. Neurobiol Aging. 2012. PMID: 22300950
Inflammatory proteins in plasma are associated with severity of Alzheimer's disease.
Leung R, Proitsi P, Simmons A, Lunnon K, Güntert A, Kronenberg D, Pritchard M, Tsolaki M, Mecocci P, Kloszewska I, Vellas B, Soininen H, Wahlund LO, Lovestone S. Leung R, et al. Among authors: pritchard m. PLoS One. 2013 Jun 10;8(6):e64971. doi: 10.1371/journal.pone.0064971. Print 2013. PLoS One. 2013. PMID: 23762274 Free PMC article.
Alleles that increase risk for type 2 diabetes mellitus are not associated with increased risk for Alzheimer's disease.
Proitsi P, Lupton MK, Velayudhan L, Hunter G, Newhouse S, Lin K, Fogh I, Tsolaki M, Daniilidou M, Pritchard M, Craig D, Todd S, Johnston JA, McGuinness B, Kloszewska I, Soininen H, Mecocci P, Vellas B, Passmore PA, Sims R, Williams J, Brayne C; Alzheimer's Disease Neuroimaging Initiative; GERAD1 Consortium; Stewart R, Sham P, Lovestone S, Powell JF. Proitsi P, et al. Among authors: pritchard m. Neurobiol Aging. 2014 Dec;35(12):2883.e3-2883.e10. doi: 10.1016/j.neurobiolaging.2014.07.023. Epub 2014 Jul 24. Neurobiol Aging. 2014. PMID: 25150574
Genetic predisposition to increased blood cholesterol and triglyceride lipid levels and risk of Alzheimer disease: a Mendelian randomization analysis.
Proitsi P, Lupton MK, Velayudhan L, Newhouse S, Fogh I, Tsolaki M, Daniilidou M, Pritchard M, Kloszewska I, Soininen H, Mecocci P, Vellas B; Alzheimer's Disease Neuroimaging Initiative; Williams J; GERAD1 Consortium; Stewart R, Sham P, Lovestone S, Powell JF. Proitsi P, et al. Among authors: pritchard m. PLoS Med. 2014 Sep 16;11(9):e1001713. doi: 10.1371/journal.pmed.1001713. eCollection 2014 Sep. PLoS Med. 2014. PMID: 25226301 Free PMC article.
653 results