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Structure of mammalian AMPK and its regulation by ADP.
Xiao B, Sanders MJ, Underwood E, Heath R, Mayer FV, Carmena D, Jing C, Walker PA, Eccleston JF, Haire LF, Saiu P, Howell SA, Aasland R, Martin SR, Carling D, Gamblin SJ. Xiao B, et al. Among authors: carling d. Nature. 2011 Apr 14;472(7342):230-3. doi: 10.1038/nature09932. Epub 2011 Mar 13. Nature. 2011. PMID: 21399626 Free PMC article.
Structural basis for AMP binding to mammalian AMP-activated protein kinase.
Xiao B, Heath R, Saiu P, Leiper FC, Leone P, Jing C, Walker PA, Haire L, Eccleston JF, Davis CT, Martin SR, Carling D, Gamblin SJ. Xiao B, et al. Among authors: carling d. Nature. 2007 Sep 27;449(7161):496-500. doi: 10.1038/nature06161. Epub 2007 Sep 12. Nature. 2007. PMID: 17851531
ADP regulates SNF1, the Saccharomyces cerevisiae homolog of AMP-activated protein kinase.
Mayer FV, Heath R, Underwood E, Sanders MJ, Carmena D, McCartney RR, Leiper FC, Xiao B, Jing C, Walker PA, Haire LF, Ogrodowicz R, Martin SR, Schmidt MC, Gamblin SJ, Carling D. Mayer FV, et al. Among authors: carling d. Cell Metab. 2011 Nov 2;14(5):707-14. doi: 10.1016/j.cmet.2011.09.009. Epub 2011 Oct 20. Cell Metab. 2011. PMID: 22019086 Free PMC article.
Structural basis of AMPK regulation by small molecule activators.
Xiao B, Sanders MJ, Carmena D, Bright NJ, Haire LF, Underwood E, Patel BR, Heath RB, Walker PA, Hallen S, Giordanetto F, Martin SR, Carling D, Gamblin SJ. Xiao B, et al. Among authors: carling d. Nat Commun. 2013;4:3017. doi: 10.1038/ncomms4017. Nat Commun. 2013. PMID: 24352254 Free PMC article.
AMP-activated protein kinase: also regulated by ADP?
Hardie DG, Carling D, Gamblin SJ. Hardie DG, et al. Among authors: carling d. Trends Biochem Sci. 2011 Sep;36(9):470-7. doi: 10.1016/j.tibs.2011.06.004. Epub 2011 Jul 23. Trends Biochem Sci. 2011. PMID: 21782450 Review.
199 results