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SERCA2a gene transfer decreases sarcoplasmic reticulum calcium leak and reduces ventricular arrhythmias in a model of chronic heart failure.
Lyon AR, Bannister ML, Collins T, Pearce E, Sepehripour AH, Dubb SS, Garcia E, O'Gara P, Liang L, Kohlbrenner E, Hajjar RJ, Peters NS, Poole-Wilson PA, Macleod KT, Harding SE. Lyon AR, et al. Among authors: kohlbrenner e. Circ Arrhythm Electrophysiol. 2011 Jun;4(3):362-72. doi: 10.1161/CIRCEP.110.961615. Epub 2011 Mar 15. Circ Arrhythm Electrophysiol. 2011. PMID: 21406682 Free PMC article.
Plasticity of surface structures and β(2)-adrenergic receptor localization in failing ventricular cardiomyocytes during recovery from heart failure.
Lyon AR, Nikolaev VO, Miragoli M, Sikkel MB, Paur H, Benard L, Hulot JS, Kohlbrenner E, Hajjar RJ, Peters NS, Korchev YE, Macleod KT, Harding SE, Gorelik J. Lyon AR, et al. Among authors: kohlbrenner e. Circ Heart Fail. 2012 May 1;5(3):357-65. doi: 10.1161/CIRCHEARTFAILURE.111.964692. Epub 2012 Mar 28. Circ Heart Fail. 2012. PMID: 22456061 Free PMC article.
CXCR4 gene transfer prevents pressure overload induced heart failure.
Larocca TJ, Jeong D, Kohlbrenner E, Lee A, Chen J, Hajjar RJ, Tarzami ST. Larocca TJ, et al. Among authors: kohlbrenner e. J Mol Cell Cardiol. 2012 Aug;53(2):223-32. doi: 10.1016/j.yjmcc.2012.05.016. Epub 2012 Jun 3. J Mol Cell Cardiol. 2012. PMID: 22668785 Free PMC article.
Cardiac surgical delivery of the sarcoplasmic reticulum calcium ATPase rescues myocytes in ischemic heart failure.
Fargnoli AS, Katz MG, Yarnall C, Isidro A, Petrov M, Steuerwald N, Ghosh S, Richardville KC, Hillesheim R, Williams RD, Kohlbrenner E, Stedman HH, Hajjar RJ, Bridges CR. Fargnoli AS, et al. Among authors: kohlbrenner e. Ann Thorac Surg. 2013 Aug;96(2):586-95. doi: 10.1016/j.athoracsur.2013.04.021. Epub 2013 Jun 15. Ann Thorac Surg. 2013. PMID: 23773730 Free PMC article.
Therapeutic efficacy of AAV1.SERCA2a in monocrotaline-induced pulmonary arterial hypertension.
Hadri L, Kratlian RG, Benard L, Maron BA, Dorfmüller P, Ladage D, Guignabert C, Ishikawa K, Aguero J, Ibanez B, Turnbull IC, Kohlbrenner E, Liang L, Zsebo K, Humbert M, Hulot JS, Kawase Y, Hajjar RJ, Leopold JA. Hadri L, et al. Among authors: kohlbrenner e. Circulation. 2013 Jul 30;128(5):512-23. doi: 10.1161/CIRCULATIONAHA.113.001585. Epub 2013 Jun 26. Circulation. 2013. PMID: 23804254 Free PMC article.
Cardiac Stim1 Silencing Impairs Adaptive Hypertrophy and Promotes Heart Failure Through Inactivation of mTORC2/Akt Signaling.
Bénard L, Oh JG, Cacheux M, Lee A, Nonnenmacher M, Matasic DS, Kohlbrenner E, Kho C, Pavoine C, Hajjar RJ, Hulot JS. Bénard L, et al. Among authors: kohlbrenner e. Circulation. 2016 Apr 12;133(15):1458-71; discussion 1471. doi: 10.1161/CIRCULATIONAHA.115.020678. Epub 2016 Mar 2. Circulation. 2016. PMID: 26936863 Free PMC article.
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