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SERCA2a gene transfer decreases sarcoplasmic reticulum calcium leak and reduces ventricular arrhythmias in a model of chronic heart failure.
Lyon AR, Bannister ML, Collins T, Pearce E, Sepehripour AH, Dubb SS, Garcia E, O'Gara P, Liang L, Kohlbrenner E, Hajjar RJ, Peters NS, Poole-Wilson PA, Macleod KT, Harding SE. Lyon AR, et al. Among authors: liang l. Circ Arrhythm Electrophysiol. 2011 Jun;4(3):362-72. doi: 10.1161/CIRCEP.110.961615. Epub 2011 Mar 15. Circ Arrhythm Electrophysiol. 2011. PMID: 21406682 Free PMC article.
Therapeutic efficacy of AAV1.SERCA2a in monocrotaline-induced pulmonary arterial hypertension.
Hadri L, Kratlian RG, Benard L, Maron BA, Dorfmüller P, Ladage D, Guignabert C, Ishikawa K, Aguero J, Ibanez B, Turnbull IC, Kohlbrenner E, Liang L, Zsebo K, Humbert M, Hulot JS, Kawase Y, Hajjar RJ, Leopold JA. Hadri L, et al. Among authors: liang l. Circulation. 2013 Jul 30;128(5):512-23. doi: 10.1161/CIRCULATIONAHA.113.001585. Epub 2013 Jun 26. Circulation. 2013. PMID: 23804254 Free PMC article.
Transcoronary gene transfer of SERCA2a increases coronary blood flow and decreases cardiomyocyte size in a type 2 diabetic rat model.
Sakata S, Lebeche D, Sakata Y, Sakata N, Chemaly ER, Liang L, Nakajima-Takenaka C, Tsuji T, Konishi N, del Monte F, Hajjar RJ, Takaki M. Sakata S, et al. Among authors: liang l. Am J Physiol Heart Circ Physiol. 2007 Feb;292(2):H1204-7. doi: 10.1152/ajpheart.00892.2006. Epub 2006 Sep 29. Am J Physiol Heart Circ Physiol. 2007. PMID: 17012346 Free article.
Long-term cardiac-targeted RNA interference for the treatment of heart failure restores cardiac function and reduces pathological hypertrophy.
Suckau L, Fechner H, Chemaly E, Krohn S, Hadri L, Kockskämper J, Westermann D, Bisping E, Ly H, Wang X, Kawase Y, Chen J, Liang L, Sipo I, Vetter R, Weger S, Kurreck J, Erdmann V, Tschope C, Pieske B, Lebeche D, Schultheiss HP, Hajjar RJ, Poller WC. Suckau L, et al. Among authors: liang l. Circulation. 2009 Mar 10;119(9):1241-52. doi: 10.1161/CIRCULATIONAHA.108.783852. Epub 2009 Feb 23. Circulation. 2009. PMID: 19237664 Free PMC article.
A new model of congestive heart failure in rats.
Chen J, Chemaly ER, Liang LF, LaRocca TJ, Yaniz-Galende E, Hajjar RJ. Chen J, et al. Am J Physiol Heart Circ Physiol. 2011 Sep;301(3):H994-1003. doi: 10.1152/ajpheart.00245.2011. Epub 2011 Jun 17. Am J Physiol Heart Circ Physiol. 2011. PMID: 21685270 Free PMC article.
Synergistic role of protein phosphatase inhibitor 1 and sarco/endoplasmic reticulum Ca2+ -ATPase in the acquisition of the contractile phenotype of arterial smooth muscle cells.
Lipskaia L, Bobe R, Chen J, Turnbull IC, Lopez JJ, Merlet E, Jeong D, Karakikes I, Ross AS, Liang L, Mougenot N, Atassi F, Lompré AM, Tarzami ST, Kovacic JC, Kranias E, Hajjar RJ, Hadri L. Lipskaia L, et al. Among authors: liang l. Circulation. 2014 Feb 18;129(7):773-85. doi: 10.1161/CIRCULATIONAHA.113.002565. Epub 2013 Nov 18. Circulation. 2014. PMID: 24249716 Free PMC article.
The role of SUMO-1 in cardiac oxidative stress and hypertrophy.
Lee A, Jeong D, Mitsuyama S, Oh JG, Liang L, Ikeda Y, Sadoshima J, Hajjar RJ, Kho C. Lee A, et al. Among authors: liang l. Antioxid Redox Signal. 2014 Nov 10;21(14):1986-2001. doi: 10.1089/ars.2014.5983. Epub 2014 Aug 4. Antioxid Redox Signal. 2014. PMID: 24893265 Free PMC article.
Ischemic Model of Heart Failure in Rats and Mice.
Chen J, Ceholski DK, Turnbull IC, Liang L, Hajjar RJ. Chen J, et al. Among authors: liang l. Methods Mol Biol. 2018;1816:175-182. doi: 10.1007/978-1-4939-8597-5_13. Methods Mol Biol. 2018. PMID: 29987819
8,475 results