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A phase I trial to evaluate the safety and pharmacokinetics of low-dose methotrexate as an anti-malarial drug in Kenyan adult healthy volunteers.
Chilengi R, Juma R, Abdallah AM, Bashraheil M, Lodenyo H, Nyakundi P, Anabwani E, Salim A, Mwambingu G, Wenwa E, Jemutai J, Kipkeu C, Oyoo GO, Muchohi SN, Kokwaro G, Niehues T, Lang T, Nzila A. Chilengi R, et al. Malar J. 2011 Mar 16;10:63. doi: 10.1186/1475-2875-10-63. Malar J. 2011. PMID: 21410944 Free PMC article. Clinical Trial.
Anticancer agents against malaria: time to revisit?
Nzila A, Okombo J, Becker RP, Chilengi R, Lang T, Niehues T. Nzila A, et al. Among authors: chilengi r. Trends Parasitol. 2010 Mar;26(3):125-9. doi: 10.1016/j.pt.2009.12.002. Epub 2010 Jan 6. Trends Parasitol. 2010. PMID: 20056487 Free PMC article.
Lessons learnt from the first controlled human malaria infection study conducted in Nairobi, Kenya.
Hodgson SH, Juma E, Salim A, Magiri C, Njenga D, Molyneux S, Njuguna P, Awuondo K, Lowe B, Billingsley PF, Cole AO, Ogwang C, Osier F, Chilengi R, Hoffman SL, Draper SJ, Ogutu B, Marsh K. Hodgson SH, et al. Among authors: chilengi r. Malar J. 2015 Apr 28;14:182. doi: 10.1186/s12936-015-0671-x. Malar J. 2015. PMID: 25927522 Free PMC article. Clinical Trial.
Phase 1 randomized controlled trial to evaluate the safety and immunogenicity of recombinant Pichia pastoris-expressed Plasmodium falciparum apical membrane antigen 1 (PfAMA1-FVO [25-545]) in healthy Malian adults in Bandiagara.
Thera MA, Coulibaly D, Kone AK, Guindo AB, Traore K, Sall AH, Diarra I, Daou M, Traore IM, Tolo Y, Sissoko M, Niangaly A, Arama C, Baby M, Kouriba B, Sissoko MS, Sagara I, Toure OB, Dolo A, Diallo DA, Remarque E, Chilengi R, Noor R, Sesay S, Thomas A, Kocken CH, Faber BW, Imoukhuede EB, Leroy O, Doumbo OK. Thera MA, et al. Among authors: chilengi r. Malar J. 2016 Aug 30;15(1):442. doi: 10.1186/s12936-016-1466-4. Malar J. 2016. PMID: 27577237 Free PMC article. Clinical Trial.
Data safety and monitoring boards for African clinical trials.
Lang T, Chilengi R, Noor RA, Ogutu B, Todd JE, Kilama WL, Targett GA. Lang T, et al. Among authors: chilengi r. Trans R Soc Trop Med Hyg. 2008 Dec;102(12):1189-94. doi: 10.1016/j.trstmh.2008.06.009. Epub 2008 Jul 21. Trans R Soc Trop Med Hyg. 2008. PMID: 18644610
Mortality after fluid bolus in African children with severe infection.
Maitland K, Kiguli S, Opoka RO, Engoru C, Olupot-Olupot P, Akech SO, Nyeko R, Mtove G, Reyburn H, Lang T, Brent B, Evans JA, Tibenderana JK, Crawley J, Russell EC, Levin M, Babiker AG, Gibb DM; FEAST Trial Group. Maitland K, et al. N Engl J Med. 2011 Jun 30;364(26):2483-95. doi: 10.1056/NEJMoa1101549. Epub 2011 May 26. N Engl J Med. 2011. PMID: 21615299 Free article. Clinical Trial.
Clinical laboratory reference values amongst children aged 4 weeks to 17 months in Kilifi, Kenya: A cross sectional observational study.
Gitaka J, Ogwang C, Ngari M, Akoo P, Olotu A, Kerubo C, Fegan G, Njuguna P, Nyakaya G, Otieno T, Mwambingu G, Awuondo K, Lowe B, Chilengi R, Berkley JA. Gitaka J, et al. Among authors: chilengi r. PLoS One. 2017 May 11;12(5):e0177382. doi: 10.1371/journal.pone.0177382. eCollection 2017. PLoS One. 2017. PMID: 28493930 Free PMC article.
163 results