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Signaling by the tyrosine kinase Yes promotes liver cancer development.
Guégan JP, Lapouge M, Voisin L, Saba-El-Leil MK, Tanguay PL, Lévesque K, Brégeon J, Mes-Masson AM, Lamarre D, Haibe-Kains B, Trinh VQ, Soucy G, Bilodeau M, Meloche S. Guégan JP, et al. Sci Signal. 2022 Jan 18;15(717):eabj4743. doi: 10.1126/scisignal.abj4743. Epub 2022 Jan 18. Sci Signal. 2022. PMID: 35041461
Disrupting the CD95-PLCγ1 interaction prevents Th17-driven inflammation.
Poissonnier A, Guégan JP, Nguyen HT, Best D, Levoin N, Kozlov G, Gehring K, Pineau R, Jouan F, Morere L, Martin S, Thomas M, Lazaro E, Douchet I, Ducret T, van de Weghe P, Blanco P, Jean M, Vacher P, Legembre P. Poissonnier A, et al. Among authors: guegan jp. Nat Chem Biol. 2018 Dec;14(12):1079-1089. doi: 10.1038/s41589-018-0162-9. Epub 2018 Nov 14. Nat Chem Biol. 2018. PMID: 30429604
HIV protease inhibitors and autoimmunity: An odd, but promising idea.
Galli G, Poissonnier A, Guégan JP, Charrier M, Sisirak V, Lazaro E, Truchetet ME, Richez C, Legembre P, Blanco P. Galli G, et al. Among authors: guegan jp. Autoimmun Rev. 2019 Oct;18(10):102370. doi: 10.1016/j.autrev.2019.102370. Epub 2019 Aug 9. Autoimmun Rev. 2019. PMID: 31404704 No abstract available.
53 results