Miller RR - Search Results

1

Discovery of a piperazine urea based compound as a potent, selective, orally bioavailable melanocortin subtype-4 receptor partial agonist.

Hong Q, Bakshi RK, Palucki BL, Park MK, Ye Z, He S, Pollard PG, Sebhat IK, Liu J, Guo L, Cashen DE, Martin WJ, Weinberg DH, MacNeil T, Tang R, Tamvakopoulos C, Peng Q, Miller RR, Stearns RA, Chen HY, Chen AS, Strack AM, Fong TM, MacIntyre DE, Wyvratt MJ, Nargund RP. Hong Q, et al. Among authors: miller rr. Bioorg Med Chem Lett. 2011 Apr 15;21(8):2330-4. doi: 10.1016/j.bmcl.2011.02.090. Epub 2011 Mar 1. Bioorg Med Chem Lett. 2011. PMID: 21439820

2

The metabolism of DuP 753, a nonpeptide angiotensin II receptor antagonist, by rat, monkey, and human liver slices.

Stearns RA, Miller RR, Doss GA, Chakravarty PK, Rosegay A, Gatto GJ, Chiu SH. Stearns RA, et al. Among authors: miller rr. Drug Metab Dispos. 1992 Mar-Apr;20(2):281-7. Drug Metab Dispos. 1992. PMID: 1352222

3

Synthesis and identification of a novel tetrazole metabolite of the angiotensin II receptor antagonist DuP 753.

Stearns RA, Doss GA, Miller RR, Chiu SH. Stearns RA, et al. Among authors: miller rr. Drug Metab Dispos. 1991 Nov-Dec;19(6):1160-2. Drug Metab Dispos. 1991. PMID: 1687025 No abstract available.

4

Metabolites of L-735,524, a potent HIV-1 protease inhibitor, in human urine.

Balani SK, Arison BH, Mathai L, Kauffman LR, Miller RR, Stearns RA, Chen IW, Lin JH. Balani SK, et al. Among authors: miller rr. Drug Metab Dispos. 1995 Feb;23(2):266-70. Drug Metab Dispos. 1995. PMID: 7736923 Clinical Trial.

5

Absorption and glucuronidation of the angiotensin II receptor antagonist losartan by the rat intestine.

Krieter PA, Colletti AE, Miller RR, Stearns RA. Krieter PA, et al. Among authors: miller rr. J Pharmacol Exp Ther. 1995 May;273(2):816-22. J Pharmacol Exp Ther. 1995. PMID: 7752085

6

Evidence for a 1,2-hydride shift in the microsomal metabolism of the heterocycle L-158,338, a nonpeptide angiotensin II receptor antagonist.

Stearns RA, Miller RR, Arison BH, Rosegay A, Smith JL, Mantlo NB, Chiu SH. Stearns RA, et al. Among authors: miller rr. Drug Metab Dispos. 1993 Jul-Aug;21(4):670-6. Drug Metab Dispos. 1993. PMID: 8104127

7

Pharmacokinetics and disposition of L-692,429. A novel nonpeptidyl growth hormone secretagogue in preclinical species.

Leung KH, Cohn DA, Miller RR, Doss GA, Stearns RA, Simpson RE, Feeney WP, Chiu SH. Leung KH, et al. Among authors: miller rr. Drug Metab Dispos. 1996 Jul;24(7):753-60. Drug Metab Dispos. 1996. PMID: 8818572

8

A selective human beta3 adrenergic receptor agonist increases metabolic rate in rhesus monkeys.

Fisher MH, Amend AM, Bach TJ, Barker JM, Brady EJ, Candelore MR, Carroll D, Cascieri MA, Chiu SH, Deng L, Forrest MJ, Hegarty-Friscino B, Guan XM, Hom GJ, Hutchins JE, Kelly LJ, Mathvink RJ, Metzger JM, Miller RR, Ok HO, Parmee ER, Saperstein R, Strader CD, Stearns RA, MacIntyre DE, et al. Fisher MH, et al. Among authors: miller rr. J Clin Invest. 1998 Jun 1;101(11):2387-93. doi: 10.1172/JCI2496. J Clin Invest. 1998. PMID: 9616210 Free PMC article.

9

Disposition of L-732,531, a potent immunosuppressant, in rats and baboons.

Karanam BV, Miller RR, Colletti A, Montgomery T, Carey KD, Hawkins T, Tang YS, Lavin M, Stearns RA, Chiu SH, Vincent SH. Karanam BV, et al. Among authors: miller rr. Drug Metab Dispos. 1998 Oct;26(10):949-57. Drug Metab Dispos. 1998. PMID: 9763399

10

3-Pyridyloxypropanolamine agonists of the beta 3 adrenergic receptor with improved pharmacokinetic properties.

Weber AE, Ok HO, Alvaro RF, Candelore MR, Cascieri MA, Chiu SH, Deng L, Forrest MJ, Hom GJ, Hutchins JE, Kao J, MacIntyre DE, Mathvink RJ, McLoughlin D, Miller RR, Newbold RC, Olah TV, Parmee ER, Perkins L, Stearns RA, Strader CD, Szumiloski J, Tang YS, Tota L, Fisher MH, et al. Weber AE, et al. Among authors: miller rr. Bioorg Med Chem Lett. 1998 Aug 18;8(16):2111-6. doi: 10.1016/s0960-894x(98)00381-3. Bioorg Med Chem Lett. 1998. PMID: 9873496

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