Evangelista M - Search Results

1

Discovery and molecular characterization of a Bcl-2-regulated cell death pathway in schistosomes.

Lee EF, Clarke OB, Evangelista M, Feng Z, Speed TP, Tchoubrieva EB, Strasser A, Kalinna BH, Colman PM, Fairlie WD. Lee EF, et al. Among authors: evangelista m. Proc Natl Acad Sci U S A. 2011 Apr 26;108(17):6999-7003. doi: 10.1073/pnas.1100652108. Epub 2011 Mar 28. Proc Natl Acad Sci U S A. 2011. PMID: 21444803 Free PMC article.

2

Structural basis of Bcl-xL recognition by a BH3-mimetic α/β-peptide generated by sequence-based design.

Lee EF, Smith BJ, Horne WS, Mayer KN, Evangelista M, Colman PM, Gellman SH, Fairlie WD. Lee EF, et al. Among authors: evangelista m. Chembiochem. 2011 Sep 5;12(13):2025-32. doi: 10.1002/cbic.201100314. Epub 2011 Jul 8. Chembiochem. 2011. PMID: 21744457 Free PMC article.

3

Crystal structure of a BCL-W domain-swapped dimer: implications for the function of BCL-2 family proteins.

Lee EF, Dewson G, Smith BJ, Evangelista M, Pettikiriarachchi A, Dogovski C, Perugini MA, Colman PM, Fairlie WD. Lee EF, et al. Among authors: evangelista m. Structure. 2011 Oct 12;19(10):1467-76. doi: 10.1016/j.str.2011.07.015. Structure. 2011. PMID: 22000515 Free article.

4

Structure-guided rational design of α/β-peptide foldamers with high affinity for BCL-2 family prosurvival proteins.

Smith BJ, Lee EF, Checco JW, Evangelista M, Gellman SH, Fairlie WD. Smith BJ, et al. Among authors: evangelista m. Chembiochem. 2013 Sep 2;14(13):1564-72. doi: 10.1002/cbic.201300351. Epub 2013 Aug 8. Chembiochem. 2013. PMID: 23929624 Free PMC article.

5

The functional differences between pro-survival and pro-apoptotic B cell lymphoma 2 (Bcl-2) proteins depend on structural differences in their Bcl-2 homology 3 (BH3) domains.

Lee EF, Dewson G, Evangelista M, Pettikiriarachchi A, Gold GJ, Zhu H, Colman PM, Fairlie WD. Lee EF, et al. Among authors: evangelista m. J Biol Chem. 2014 Dec 26;289(52):36001-17. doi: 10.1074/jbc.M114.610758. Epub 2014 Nov 3. J Biol Chem. 2014. PMID: 25371206 Free PMC article.

6

A transgenic mouse model to inducibly target prosurvival Bcl2 proteins with selective BH3 peptides in vivo.

Lee EF, Takiguchi M, Pettikiriarachchi A, Evangelista M, Huang DC, Dickins RA, Fairlie WD. Lee EF, et al. Among authors: evangelista m. Cell Death Dis. 2015 Mar 12;6(3):e1679. doi: 10.1038/cddis.2015.54. Cell Death Dis. 2015. PMID: 25766318 Free PMC article. No abstract available.

7

Bid chimeras indicate that most BH3-only proteins can directly activate Bak and Bax, and show no preference for Bak versus Bax.

Hockings C, Anwari K, Ninnis RL, Brouwer J, O'Hely M, Evangelista M, Hinds MG, Czabotar PE, Lee EF, Fairlie WD, Dewson G, Kluck RM. Hockings C, et al. Among authors: evangelista m. Cell Death Dis. 2015 Apr 23;6(4):e1735. doi: 10.1038/cddis.2015.105. Cell Death Dis. 2015. PMID: 25906158 Free PMC article.

8

α/β-Peptide Foldamers Targeting Intracellular Protein-Protein Interactions with Activity in Living Cells.

Checco JW, Lee EF, Evangelista M, Sleebs NJ, Rogers K, Pettikiriarachchi A, Kershaw NJ, Eddinger GA, Belair DG, Wilson JL, Eller CH, Raines RT, Murphy WL, Smith BJ, Gellman SH, Fairlie WD. Checco JW, et al. Among authors: evangelista m. J Am Chem Soc. 2015 Sep 9;137(35):11365-75. doi: 10.1021/jacs.5b05896. Epub 2015 Aug 28. J Am Chem Soc. 2015. PMID: 26317395 Free PMC article.

9

The BECN1 N-terminal domain is intrinsically disordered.

Lee EF, Perugini MA, Pettikiriarachchi A, Evangelista M, Keizer DW, Yao S, Fairlie WD. Lee EF, et al. Among authors: evangelista m. Autophagy. 2016;12(3):460-71. doi: 10.1080/15548627.2016.1140292. Autophagy. 2016. PMID: 27046249 Free PMC article.

10

Physiological restraint of Bak by Bcl-xL is essential for cell survival.

Lee EF, Grabow S, Chappaz S, Dewson G, Hockings C, Kluck RM, Debrincat MA, Gray DH, Witkowski MT, Evangelista M, Pettikiriarachchi A, Bouillet P, Lane RM, Czabotar PE, Colman PM, Smith BJ, Kile BT, Fairlie WD. Lee EF, et al. Among authors: evangelista m. Genes Dev. 2016 May 15;30(10):1240-50. doi: 10.1101/gad.279414.116. Epub 2016 May 19. Genes Dev. 2016. PMID: 27198225 Free PMC article.

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