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CXCR2 and CXCL4 regulate survival and self-renewal of hematopoietic stem/progenitor cells.
Sinclair A, Park L, Shah M, Drotar M, Calaminus S, Hopcroft LE, Kinstrie R, Guitart AV, Dunn K, Abraham SA, Sansom O, Michie AM, Machesky L, Kranc KR, Graham GJ, Pellicano F, Holyoake TL. Sinclair A, et al. Among authors: kinstrie r. Blood. 2016 Jul 21;128(3):371-83. doi: 10.1182/blood-2015-08-661785. Epub 2016 May 24. Blood. 2016. PMID: 27222476 Free PMC article.
Epigenetic Reprogramming Sensitizes CML Stem Cells to Combined EZH2 and Tyrosine Kinase Inhibition.
Scott MT, Korfi K, Saffrey P, Hopcroft LE, Kinstrie R, Pellicano F, Guenther C, Gallipoli P, Cruz M, Dunn K, Jorgensen HG, Cassels JE, Hamilton A, Crossan A, Sinclair A, Holyoake TL, Vetrie D. Scott MT, et al. Among authors: kinstrie r. Cancer Discov. 2016 Nov;6(11):1248-1257. doi: 10.1158/2159-8290.CD-16-0263. Epub 2016 Sep 14. Cancer Discov. 2016. PMID: 27630125 Free PMC article.
CD93 is expressed on chronic myeloid leukemia stem cells and identifies a quiescent population which persists after tyrosine kinase inhibitor therapy.
Kinstrie R, Horne GA, Morrison H, Irvine D, Munje C, Castañeda EG, Moka HA, Dunn K, Cassels JE, Parry N, Clarke CJ, Scott MT, Clark RE, Holyoake TL, Wheadon H, Copland M. Kinstrie R, et al. Leukemia. 2020 Jun;34(6):1613-1625. doi: 10.1038/s41375-019-0684-5. Epub 2020 Jan 2. Leukemia. 2020. PMID: 31896780 Free PMC article.
Correction: CD93 is expressed on chronic myeloid leukemia stem cells and identifies a quiescent population which persists after tyrosine kinase inhibitor therapy.
Kinstrie R, Horne GA, Morrison H, Irvine D, Munje C, Castañeda EG, Moka HA, Dunn K, Cassels JE, Parry N, Clarke CJ, Scott MT, Clark RE, Holyoake TL, Wheadon H, Copland M. Kinstrie R, et al. Leukemia. 2020 Jul;34(7):1975. doi: 10.1038/s41375-020-0721-4. Leukemia. 2020. PMID: 32005922 Free PMC article.
Episomal amplification of NUP214-ABL1 fusion gene in B-cell acute lymphoblastic leukemia.
Eyre T, Schwab CJ, Kinstrie R, McGuire AK, Strefford J, Peniket A, Mead A, Littlewood T, Holyoake TL, Copland M, Moorman AV, Harrison CJ, Vyas P. Eyre T, et al. Among authors: kinstrie r. Blood. 2012 Nov 22;120(22):4441-3. doi: 10.1182/blood-2012-09-456517. Blood. 2012. PMID: 23175662 Free article. No abstract available.
Novel drug therapies in myeloid leukemia.
Horne GA, Kinstrie R, Copland M. Horne GA, et al. Among authors: kinstrie r. Pharm Pat Anal. 2015;4(3):187-205. doi: 10.4155/ppa.15.3. Pharm Pat Anal. 2015. PMID: 26030080 Free article. Review.
Targeting chronic myeloid leukemia stem cells.
Kinstrie R, Copland M. Kinstrie R, et al. Curr Hematol Malig Rep. 2013 Mar;8(1):14-21. doi: 10.1007/s11899-012-0148-8. Curr Hematol Malig Rep. 2013. PMID: 23264204 Review.
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