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Methodology and early findings of the Diabetes Management Project: a cohort study investigating the barriers to optimal diabetes care in diabetic patients with and without diabetic retinopathy.
Lamoureux EL, Fenwick E, Xie J, Mcauley A, Nicolaou T, Larizza M, Rees G, Qureshi S, Wong TY, Benarous R, Dirani M. Lamoureux EL, et al. Among authors: benarous r. Clin Exp Ophthalmol. 2012 Jan-Feb;40(1):73-82. doi: 10.1111/j.1442-9071.2011.02697.x. Epub 2011 Nov 4. Clin Exp Ophthalmol. 2012. PMID: 21902788
Biological and Structural Analyses of New Potent Allosteric Inhibitors of HIV-1 Integrase.
Bonnard D, Le Rouzic E, Singer MR, Yu Z, Le Strat F, Batisse C, Batisse J, Amadori C, Chasset S, Pye VE, Emiliani S, Ledoussal B, Ruff M, Moreau F, Cherepanov P, Benarous R. Bonnard D, et al. Among authors: benarous r. Antimicrob Agents Chemother. 2023 Jul 18;67(7):e0046223. doi: 10.1128/aac.00462-23. Epub 2023 Jun 13. Antimicrob Agents Chemother. 2023. PMID: 37310224 Free PMC article.
Structure-function analyses unravel distinct effects of allosteric inhibitors of HIV-1 integrase on viral maturation and integration.
Bonnard D, Le Rouzic E, Eiler S, Amadori C, Orlov I, Bruneau JM, Brias J, Barbion J, Chevreuil F, Spehner D, Chasset S, Ledoussal B, Moreau F, Saïb A, Klaholz BP, Emiliani S, Ruff M, Zamborlini A, Benarous R. Bonnard D, et al. Among authors: benarous r. J Biol Chem. 2018 Apr 20;293(16):6172-6186. doi: 10.1074/jbc.M117.816793. Epub 2018 Mar 5. J Biol Chem. 2018. PMID: 29507092 Free PMC article.
The HIV-1 integrase-LEDGF allosteric inhibitor MUT-A: resistance profile, impairment of virus maturation and infectivity but without influence on RNA packaging or virus immunoreactivity.
Amadori C, van der Velden YU, Bonnard D, Orlov I, van Bel N, Le Rouzic E, Miralles L, Brias J, Chevreuil F, Spehner D, Chasset S, Ledoussal B, Mayr L, Moreau F, García F, Gatell J, Zamborlini A, Emiliani S, Ruff M, Klaholz BP, Moog C, Berkhout B, Plana M, Benarous R. Amadori C, et al. Among authors: benarous r. Retrovirology. 2017 Nov 9;14(1):50. doi: 10.1186/s12977-017-0373-2. Retrovirology. 2017. PMID: 29121950 Free PMC article.
Dual inhibition of HIV-1 replication by integrase-LEDGF allosteric inhibitors is predominant at the post-integration stage.
Le Rouzic E, Bonnard D, Chasset S, Bruneau JM, Chevreuil F, Le Strat F, Nguyen J, Beauvoir R, Amadori C, Brias J, Vomscheid S, Eiler S, Lévy N, Delelis O, Deprez E, Saïb A, Zamborlini A, Emiliani S, Ruff M, Ledoussal B, Moreau F, Benarous R. Le Rouzic E, et al. Among authors: benarous r. Retrovirology. 2013 Nov 21;10:144. doi: 10.1186/1742-4690-10-144. Retrovirology. 2013. PMID: 24261564 Free PMC article.
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