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Page 1
Discovery of small molecule human FPR1 receptor antagonists.
Unitt J, Fagura M, Phillips T, King S, Perry M, Morley A, MacDonald C, Weaver R, Christie J, Barber S, Mohammed R, Paul M, Cook A, Baxter A. Unitt J, et al. Among authors: baxter a. Bioorg Med Chem Lett. 2011 May 15;21(10):2991-7. doi: 10.1016/j.bmcl.2011.03.049. Epub 2011 Mar 21. Bioorg Med Chem Lett. 2011. PMID: 21486695
Discovery of small molecule human C5a receptor antagonists.
Sanganee HJ, Baxter A, Barber S, Brown AJ, Grice D, Hunt F, King S, Laughton D, Pairaudeau G, Thong B, Weaver R, Unitt J. Sanganee HJ, et al. Among authors: baxter a. Bioorg Med Chem Lett. 2009 Feb 15;19(4):1143-7. doi: 10.1016/j.bmcl.2008.12.104. Epub 2008 Dec 31. Bioorg Med Chem Lett. 2009. PMID: 19171482
Novel P2X7 receptor antagonists.
Alcaraz L, Baxter A, Bent J, Bowers K, Braddock M, Cladingboel D, Donald D, Fagura M, Furber M, Laurent C, Lawson M, Mortimore M, McCormick M, Roberts N, Robertson M. Alcaraz L, et al. Among authors: baxter a. Bioorg Med Chem Lett. 2003 Nov 17;13(22):4043-6. doi: 10.1016/j.bmcl.2003.08.033. Bioorg Med Chem Lett. 2003. PMID: 14592504
Non-covalent inhibitors of rhinovirus 3C protease.
Baxter A, Chambers M, Edfeldt F, Edman K, Freeman A, Johansson C, King S, Morley A, Petersen J, Rawlins P, Spadola L, Thong B, Van de Poël H, Williams N. Baxter A, et al. Bioorg Med Chem Lett. 2011 Jan 15;21(2):777-80. doi: 10.1016/j.bmcl.2010.11.110. Epub 2010 Nov 26. Bioorg Med Chem Lett. 2011. PMID: 21183345
Discovery of AZD-2098 and AZD-1678, Two Potent and Bioavailable CCR4 Receptor Antagonists.
Kindon N, Andrews G, Baxter A, Cheshire D, Hemsley P, Johnson T, Liu YZ, McGinnity D, McHale M, Mete A, Reuberson J, Roberts B, Steele J, Teobald B, Unitt J, Vaughan D, Walters I, Stocks MJ. Kindon N, et al. Among authors: baxter a. ACS Med Chem Lett. 2017 Sep 1;8(9):981-986. doi: 10.1021/acsmedchemlett.7b00315. eCollection 2017 Sep 14. ACS Med Chem Lett. 2017. PMID: 28947948 Free PMC article.
671 results