Mills GB - Search Results

1

PI3K pathway mutations and PTEN levels in primary and metastatic breast cancer.

Gonzalez-Angulo AM, Ferrer-Lozano J, Stemke-Hale K, Sahin A, Liu S, Barrera JA, Burgues O, Lluch AM, Chen H, Hortobagyi GN, Mills GB, Meric-Bernstam F. Gonzalez-Angulo AM, et al. Among authors: mills gb. Mol Cancer Ther. 2011 Jun;10(6):1093-101. doi: 10.1158/1535-7163.MCT-10-1089. Epub 2011 Apr 13. Mol Cancer Ther. 2011. PMID: 21490305 Free PMC article.

2

Adenoviral transgene expression of MMAC/PTEN in human glioma cells inhibits Akt activation and induces anoikis.

Davies MA, Lu Y, Sano T, Fang X, Tang P, LaPushin R, Koul D, Bookstein R, Stokoe D, Yung WK, Mills GB, Steck PA. Davies MA, et al. Among authors: mills gb. Cancer Res. 1998 Dec 1;58(23):5285-90. Cancer Res. 1998. PMID: 9850049

3

The PTEN/MMAC1/TEP tumor suppressor gene decreases cell growth and induces apoptosis and anoikis in breast cancer cells.

Lu Y, Lin YZ, LaPushin R, Cuevas B, Fang X, Yu SX, Davies MA, Khan H, Furui T, Mao M, Zinner R, Hung MC, Steck P, Siminovitch K, Mills GB. Lu Y, et al. Among authors: mills gb. Oncogene. 1999 Nov 25;18(50):7034-45. doi: 10.1038/sj.onc.1203183. Oncogene. 1999. PMID: 10597304

4

Linking molecular therapeutics to molecular diagnostics: inhibition of the FRAP/RAFT/TOR component of the PI3K pathway preferentially blocks PTEN mutant cells in vitro and in vivo.

Mills GB, Lu Y, Kohn EC. Mills GB, et al. Proc Natl Acad Sci U S A. 2001 Aug 28;98(18):10031-3. doi: 10.1073/pnas.191379498. Proc Natl Acad Sci U S A. 2001. PMID: 11526226 Free PMC article. No abstract available.

5

The role of genetic abnormalities of PTEN and the phosphatidylinositol 3-kinase pathway in breast and ovarian tumorigenesis, prognosis, and therapy.

Mills GB, Lu Y, Fang X, Wang H, Eder A, Mao M, Swaby R, Cheng KW, Stokoe D, Siminovitch K, Jaffe R, Gray J. Mills GB, et al. Semin Oncol. 2001 Oct;28(5 Suppl 16):125-41. doi: 10.1016/s0093-7754(01)90290-8. Semin Oncol. 2001. PMID: 11706404 Review.

6

Inhibition of the phosphatidylinositol 3'-kinase-AKT pathway induces apoptosis in pancreatic carcinoma cells in vitro and in vivo.

Bondar VM, Sweeney-Gotsch B, Andreeff M, Mills GB, McConkey DJ. Bondar VM, et al. Among authors: mills gb. Mol Cancer Ther. 2002 Oct;1(12):989-97. Mol Cancer Ther. 2002. PMID: 12481421

7

Insulin-like growth factor-I inhibits progesterone receptor expression in breast cancer cells via the phosphatidylinositol 3-kinase/Akt/mammalian target of rapamycin pathway: progesterone receptor as a potential indicator of growth factor activity in breast cancer.

Cui X, Zhang P, Deng W, Oesterreich S, Lu Y, Mills GB, Lee AV. Cui X, et al. Among authors: mills gb. Mol Endocrinol. 2003 Apr;17(4):575-88. doi: 10.1210/me.2002-0318. Epub 2003 Jan 2. Mol Endocrinol. 2003. PMID: 12554765

8

Targeting the phosphatidylinositol 3-kinase/Akt pathway for enhancing breast cancer cells to radiotherapy.

Liang K, Jin W, Knuefermann C, Schmidt M, Mills GB, Ang KK, Milas L, Fan Z. Liang K, et al. Among authors: mills gb. Mol Cancer Ther. 2003 Apr;2(4):353-60. Mol Cancer Ther. 2003. PMID: 12700279

9

ARHI is a Ras-related small G-protein with a novel N-terminal extension that inhibits growth of ovarian and breast cancers.

Luo RZ, Fang X, Marquez R, Liu SY, Mills GB, Liao WS, Yu Y, Bast RC. Luo RZ, et al. Among authors: mills gb. Oncogene. 2003 May 15;22(19):2897-909. doi: 10.1038/sj.onc.1206380. Oncogene. 2003. PMID: 12771940

10

Src family protein-tyrosine kinases alter the function of PTEN to regulate phosphatidylinositol 3-kinase/AKT cascades.

Lu Y, Yu Q, Liu JH, Zhang J, Wang H, Koul D, McMurray JS, Fang X, Yung WK, Siminovitch KA, Mills GB. Lu Y, et al. Among authors: mills gb. J Biol Chem. 2003 Oct 10;278(41):40057-66. doi: 10.1074/jbc.M303621200. Epub 2003 Jul 17. J Biol Chem. 2003. PMID: 12869565 Free article.

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