Lawton MP - Search Results

1

Effects of modulating in vivo nitric oxide production on the incidence and severity of PDE4 inhibitor-induced vascular injury in Sprague-Dawley rats.

Sheth CM, Enerson BE, Peters D, Lawton MP, Weaver JL. Sheth CM, et al. Among authors: lawton mp. Toxicol Sci. 2011 Jul;122(1):7-15. doi: 10.1093/toxsci/kfr082. Epub 2011 Apr 16. Toxicol Sci. 2011. PMID: 21498876

2

The role of eNOS phosphorylation in causing drug-induced vascular injury.

Tobin GA, Zhang J, Goodwin D, Stewart S, Xu L, Knapton A, González C, Bancos S, Zhang L, Lawton MP, Enerson BE, Weaver JL. Tobin GA, et al. Among authors: lawton mp. Toxicol Pathol. 2014 Jun;42(4):709-24. doi: 10.1177/0192623314522885. Epub 2014 Apr 3. Toxicol Pathol. 2014. PMID: 24705881

3

Use of Rat Primary Mesenteric Cells for the Prediction of PDE4 Inhibitor Drug-Induced Vascular Injury.

Gosink MM, Chapin RE, Wilkie D, Davenport S, Kumpf SW, Enerson BE, Houle C, Koza-Taylor P, Wisialowski TA, Lawton MP. Gosink MM, et al. Among authors: lawton mp. Toxicol Sci. 2017 Sep 1;159(1):42-49. doi: 10.1093/toxsci/kfx113. Toxicol Sci. 2017. PMID: 28903491

4

Nonclinical safety biomarkers of drug-induced vascular injury: current status and blueprint for the future.

Mikaelian I, Cameron M, Dalmas DA, Enerson BE, Gonzalez RJ, Guionaud S, Hoffmann PK, King NM, Lawton MP, Scicchitano MS, Smith HW, Thomas RA, Weaver JL, Zabka TS; Vascular Injury Working Group of the Predictive Safety Consortium. Mikaelian I, et al. Among authors: lawton mp. Toxicol Pathol. 2014 Jun;42(4):635-57. doi: 10.1177/0192623314525686. Epub 2014 Apr 28. Toxicol Pathol. 2014. PMID: 24777748

5

Hemodynamic correlates of drug-induced vascular injury in the rat using high-frequency ultrasound imaging.

Swanson TA, Conte T, Deeley B, Portugal S, Kreeger JM, Obert LA, Joseph EC, Wisialowski TA, Sokolowski SA, Rief C, Nugent P, Lawton MP, Enerson BE. Swanson TA, et al. Among authors: lawton mp. Toxicol Pathol. 2014 Jun;42(4):784-91. doi: 10.1177/0192623314525687. Epub 2014 Mar 26. Toxicol Pathol. 2014. PMID: 24670818

6

Acute drug-induced vascular injury in beagle dogs: pathology and correlating genomic expression.

Enerson BE, Lin A, Lu B, Zhao H, Lawton MP, Floyd E. Enerson BE, et al. Among authors: lawton mp. Toxicol Pathol. 2006;34(1):27-32. doi: 10.1080/01926230500512068. Toxicol Pathol. 2006. PMID: 16507541

7

Pathway analysis using random forests classification and regression.

Pang H, Lin A, Holford M, Enerson BE, Lu B, Lawton MP, Floyd E, Zhao H. Pang H, et al. Among authors: lawton mp. Bioinformatics. 2006 Aug 15;22(16):2028-36. doi: 10.1093/bioinformatics/btl344. Epub 2006 Jun 29. Bioinformatics. 2006. PMID: 16809386

8

Pregabalin induces hepatic hypoxia and increases endothelial cell proliferation in mice, a process inhibited by dietary vitamin E supplementation.

Criswell KA, Cook JC, Morse D, Lawton M, Somps C, Obert L, Roy M, Sokolowski S, Koza-Taylor P, Colangelo J, Navetta K, Brady J, Pegg D, Wojcinski Z, Rahbari R, Duddy S, Anderson T. Criswell KA, et al. Toxicol Sci. 2012 Jul;128(1):42-56. doi: 10.1093/toxsci/kfs148. Epub 2012 Apr 26. Toxicol Sci. 2012. PMID: 22539613

9

Utilization of causal reasoning of hepatic gene expression in rats to identify molecular pathways of idiosyncratic drug-induced liver injury.

Laifenfeld D, Qiu L, Swiss R, Park J, Macoritto M, Will Y, Younis HS, Lawton M. Laifenfeld D, et al. Toxicol Sci. 2014 Jan;137(1):234-48. doi: 10.1093/toxsci/kft232. Epub 2013 Oct 17. Toxicol Sci. 2014. PMID: 24136188

10

From the Cover: Fenretinide, Troglitazone, and Elmiron Add to Weight of Evidence Support for Hemangiosarcoma Mode-of-Action From Studies in Mice.

Cook JC, Obert LA, Koza-Taylor P, Coskran TM, Opsahl AC, Ziemek D, Roy M, Qian J, Lawton MP, Criswell KA. Cook JC, et al. Among authors: lawton mp. Toxicol Sci. 2018 Jan 1;161(1):58-75. doi: 10.1093/toxsci/kfx195. Toxicol Sci. 2018. PMID: 28973697

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