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TRIM5 is an innate immune sensor for the retrovirus capsid lattice.
Pertel T, Hausmann S, Morger D, Züger S, Guerra J, Lascano J, Reinhard C, Santoni FA, Uchil PD, Chatel L, Bisiaux A, Albert ML, Strambio-De-Castillia C, Mothes W, Pizzato M, Grütter MG, Luban J. Pertel T, et al. Among authors: chatel l. Nature. 2011 Apr 21;472(7343):361-5. doi: 10.1038/nature09976. Nature. 2011. PMID: 21512573 Free PMC article.
GlycoDelete engineering of mammalian cells simplifies N-glycosylation of recombinant proteins.
Meuris L, Santens F, Elson G, Festjens N, Boone M, Dos Santos A, Devos S, Rousseau F, Plets E, Houthuys E, Malinge P, Magistrelli G, Cons L, Chatel L, Devreese B, Callewaert N. Meuris L, et al. Among authors: chatel l. Nat Biotechnol. 2014 May;32(5):485-9. doi: 10.1038/nbt.2885. Epub 2014 Apr 20. Nat Biotechnol. 2014. PMID: 24752077 Free PMC article.
Although IL-6 trans-signaling is sufficient to drive local immune responses, classical IL-6 signaling is obligate for the induction of T cell-mediated autoimmunity.
Lissilaa R, Buatois V, Magistrelli G, Williams AS, Jones GW, Herren S, Shang L, Malinge P, Guilhot F, Chatel L, Hatterer E, Jones SA, Kosco-Vilbois MH, Ferlin WG. Lissilaa R, et al. Among authors: chatel l. J Immunol. 2010 Nov 1;185(9):5512-21. doi: 10.4049/jimmunol.1002015. Epub 2010 Sep 24. J Immunol. 2010. PMID: 20870936
Anti-CD79 antibody induces B cell anergy that protects against autoimmunity.
Hardy IR, Anceriz N, Rousseau F, Seefeldt MB, Hatterer E, Irla M, Buatois V, Chatel LE, Getahun A, Fletcher A, Cons L, Pontini G, Hertzberg NA, Magistrelli G, Malinge P, Smith MJ, Reith W, Kosco-Vilbois MH, Ferlin WG, Cambier JC. Hardy IR, et al. Among authors: chatel le. J Immunol. 2014 Feb 15;192(4):1641-50. doi: 10.4049/jimmunol.1302672. Epub 2014 Jan 17. J Immunol. 2014. PMID: 24442438 Free PMC article.
Targeting a membrane-proximal epitope on mesothelin increases the tumoricidal activity of a bispecific antibody blocking CD47 on mesothelin-positive tumors.
Hatterer E, Chauchet X, Richard F, Barba L, Moine V, Chatel L, Broyer L, Pontini G, Bautzova T, Juan F, Calloud S, Bosson N, Charreton M, Masternak K, Buatois V, Shang L. Hatterer E, et al. Among authors: chatel l. MAbs. 2020 Jan-Dec;12(1):1739408. doi: 10.1080/19420862.2020.1739408. MAbs. 2020. PMID: 32191151 Free PMC article.
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