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Prognosis in patients with sentinel node-positive melanoma is accurately defined by the combined Rotterdam tumor load and Dewar topography criteria.
van der Ploeg AP, van Akkooi AC, Rutkowski P, Nowecki ZI, Michej W, Mitra A, Newton-Bishop JA, Cook M, van der Ploeg IM, Nieweg OE, van den Hout MF, van Leeuwen PA, Voit CA, Cataldo F, Testori A, Robert C, Hoekstra HJ, Verhoef C, Spatz A, Eggermont AM. van der Ploeg AP, et al. Among authors: van der ploeg im, van den hout mf, van akkooi ac, van leeuwen pa. J Clin Oncol. 2011 Jun 1;29(16):2206-14. doi: 10.1200/JCO.2010.31.6760. Epub 2011 Apr 25. J Clin Oncol. 2011. PMID: 21519012
The interval between primary melanoma excision and sentinel node biopsy is not associated with survival in sentinel node positive patients - An EORTC Melanoma Group study.
Oude Ophuis CM, Verhoef C, Rutkowski P, Powell BW, van der Hage JA, van Leeuwen PA, Voit CA, Testori A, Robert C, Hoekstra HJ, Grünhagen DJ, Eggermont AM, van Akkooi AC. Oude Ophuis CM, et al. Among authors: van leeuwen pa. Eur J Surg Oncol. 2016 Dec;42(12):1906-1913. doi: 10.1016/j.ejso.2016.05.012. Epub 2016 May 27. Eur J Surg Oncol. 2016. PMID: 27266406
Local Adjuvant Treatment with Low-Dose CpG-B Offers Durable Protection against Disease Recurrence in Clinical Stage I-II Melanoma: Data from Two Randomized Phase II Trials.
Koster BD, van den Hout MFCM, Sluijter BJR, Molenkamp BG, Vuylsteke RJCLM, Baars A, van Leeuwen PAM, Scheper RJ, Petrousjka van den Tol M, van den Eertwegh AJM, de Gruijl TD. Koster BD, et al. Among authors: van leeuwen pam. Clin Cancer Res. 2017 Oct 1;23(19):5679-5686. doi: 10.1158/1078-0432.CCR-17-0944. Clin Cancer Res. 2017. PMID: 28972083 Clinical Trial.
Local delivery of CpG-B and GM-CSF induces concerted activation of effector and regulatory T cells in the human melanoma sentinel lymph node.
van den Hout MF, Sluijter BJ, Santegoets SJ, van Leeuwen PA, van den Tol MP, van den Eertwegh AJ, Scheper RJ, de Gruijl TD. van den Hout MF, et al. Among authors: van den tol mp, van den eertwegh aj, van leeuwen pa. Cancer Immunol Immunother. 2016 Apr;65(4):405-15. doi: 10.1007/s00262-016-1811-z. Epub 2016 Mar 2. Cancer Immunol Immunother. 2016. PMID: 26935057 Free PMC article. Clinical Trial.
Melanoma Sequentially Suppresses Different DC Subsets in the Sentinel Lymph Node, Affecting Disease Spread and Recurrence.
van den Hout MFCM, Koster BD, Sluijter BJR, Molenkamp BG, van de Ven R, van den Eertwegh AJM, Scheper RJ, van Leeuwen PAM, van den Tol MP, de Gruijl TD. van den Hout MFCM, et al. Among authors: van leeuwen pam. Cancer Immunol Res. 2017 Nov;5(11):969-977. doi: 10.1158/2326-6066.CIR-17-0110. Epub 2017 Sep 21. Cancer Immunol Res. 2017. PMID: 28935649
Arming the Melanoma Sentinel Lymph Node through Local Administration of CpG-B and GM-CSF: Recruitment and Activation of BDCA3/CD141(+) Dendritic Cells and Enhanced Cross-Presentation.
Sluijter BJ, van den Hout MF, Koster BD, van Leeuwen PA, Schneiders FL, van de Ven R, Molenkamp BG, Vosslamber S, Verweij CL, van den Tol MP, van den Eertwegh AJ, Scheper RJ, de Gruijl TD. Sluijter BJ, et al. Among authors: van den hout mf, van de ven r, van den tol mp, van den eertwegh aj, van leeuwen pa. Cancer Immunol Res. 2015 May;3(5):495-505. doi: 10.1158/2326-6066.CIR-14-0165. Epub 2015 Jan 29. Cancer Immunol Res. 2015. PMID: 25633713 Clinical Trial.
Characterization of four conventional dendritic cell subsets in human skin-draining lymph nodes in relation to T-cell activation.
van de Ven R, van den Hout MF, Lindenberg JJ, Sluijter BJ, van Leeuwen PA, Lougheed SM, Meijer S, van den Tol MP, Scheper RJ, de Gruijl TD. van de Ven R, et al. Among authors: van den hout mf, van den tol mp, van leeuwen pa. Blood. 2011 Sep 1;118(9):2502-10. doi: 10.1182/blood-2011-03-344838. Epub 2011 Jul 12. Blood. 2011. PMID: 21750314 Free article.
Absence of Granzyme B positive tumour-infiltrating lymphocytes in primary melanoma excisional biopsies is strongly associated with the presence of sentinel lymph node metastasis.
van Houdt IS, Sluijter BJ, van Leeuwen PA, Moesbergen LM, Hooijberg E, Meijer CJ, de Gruijl TD, Oudejans JJ, Boven E. van Houdt IS, et al. Among authors: van leeuwen pa. Cell Oncol. 2009;31(5):407-13. doi: 10.3233/CLO-2009-0485. Cell Oncol. 2009. PMID: 19759420 Free PMC article.
4-1BB-mediated expansion affords superior detection of in vivo primed effector memory CD8+ T cells from melanoma sentinel lymph nodes.
Sluijter BJ, van den Hout MF, Stam AG, Lougheed SM, Suhoski MM, van den Eertwegh AJ, van den Tol MP, van Leeuwen PA, Meijer S, Scheper RJ, June CH, de Gruijl TD, Santegoets SJ. Sluijter BJ, et al. Among authors: van den hout mf, van den tol mp, van den eertwegh aj, van leeuwen pa. Clin Immunol. 2010 Nov;137(2):221-33. doi: 10.1016/j.clim.2010.07.009. Epub 2010 Aug 13. Clin Immunol. 2010. PMID: 20708974
256 results