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Novel 1H-pyrrolo[2,3-b]pyridine derivative nortopsentin analogues: synthesis and antitumor activity in peritoneal mesothelioma experimental models.
Carbone A, Pennati M, Parrino B, Lopergolo A, Barraja P, Montalbano A, Spanò V, Sbarra S, Doldi V, De Cesare M, Cirrincione G, Diana P, Zaffaroni N. Carbone A, et al. Among authors: lopergolo a. J Med Chem. 2013 Sep 12;56(17):7060-72. doi: 10.1021/jm400842x. Epub 2013 Aug 23. J Med Chem. 2013. PMID: 23919303
[1,2]Oxazolo[5,4-e]isoindoles as promising tubulin polymerization inhibitors.
Spanò V, Pennati M, Parrino B, Carbone A, Montalbano A, Lopergolo A, Zuco V, Cominetti D, Diana P, Cirrincione G, Zaffaroni N, Barraja P. Spanò V, et al. Among authors: lopergolo a. Eur J Med Chem. 2016 Nov 29;124:840-851. doi: 10.1016/j.ejmech.2016.09.013. Epub 2016 Sep 5. Eur J Med Chem. 2016. PMID: 27643641
Activation of Hsp90 Enzymatic Activity and Conformational Dynamics through Rationally Designed Allosteric Ligands.
Sattin S, Tao J, Vettoretti G, Moroni E, Pennati M, Lopergolo A, Morelli L, Bugatti A, Zuehlke A, Moses M, Prince T, Kijima T, Beebe K, Rusnati M, Neckers L, Zaffaroni N, Agard DA, Bernardi A, Colombo G. Sattin S, et al. Among authors: lopergolo a. Chemistry. 2015 Sep 21;21(39):13598-608. doi: 10.1002/chem.201502211. Epub 2015 Aug 18. Chemistry. 2015. PMID: 26286886 Free PMC article.
Anti-tumor activity of selective inhibitors of XPO1/CRM1-mediated nuclear export in diffuse malignant peritoneal mesothelioma: the role of survivin.
De Cesare M, Cominetti D, Doldi V, Lopergolo A, Deraco M, Gandellini P, Friedlander S, Landesman Y, Kauffman MG, Shacham S, Pennati M, Zaffaroni N. De Cesare M, et al. Among authors: lopergolo a. Oncotarget. 2015 May 30;6(15):13119-32. doi: 10.18632/oncotarget.3761. Oncotarget. 2015. PMID: 25948791 Free PMC article.
16 results