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Impaired Rho GTPase activation abrogates cell polarization and migration in macrophages with defective lipolysis.
Aflaki E, Balenga NA, Luschnig-Schratl P, Wolinski H, Povoden S, Chandak PG, Bogner-Strauss JG, Eder S, Konya V, Kohlwein SD, Heinemann A, Kratky D. Aflaki E, et al. Among authors: wolinski h. Cell Mol Life Sci. 2011 Dec;68(23):3933-47. doi: 10.1007/s00018-011-0688-4. Epub 2011 May 2. Cell Mol Life Sci. 2011. PMID: 21533980 Free PMC article.
Triacylglycerol accumulation activates the mitochondrial apoptosis pathway in macrophages.
Aflaki E, Radovic B, Chandak PG, Kolb D, Eisenberg T, Ring J, Fertschai I, Uellen A, Wolinski H, Kohlwein SD, Zechner R, Levak-Frank S, Sattler W, Graier WF, Malli R, Madeo F, Kratky D. Aflaki E, et al. Among authors: wolinski h. J Biol Chem. 2011 Mar 4;286(9):7418-28. doi: 10.1074/jbc.M110.175703. Epub 2011 Jan 1. J Biol Chem. 2011. PMID: 21196579 Free PMC article.
APMAP interacts with lysyl oxidase-like proteins, and disruption of Apmap leads to beneficial visceral adipose tissue expansion.
Pessentheiner AR, Huber K, Pelzmann HJ, Prokesch A, Radner FPW, Wolinski H, Lindroos-Christensen J, Hoefler G, Rülicke T, Birner-Gruenberger R, Bilban M, Bogner-Strauss JG. Pessentheiner AR, et al. Among authors: wolinski h. FASEB J. 2017 Sep;31(9):4088-4103. doi: 10.1096/fj.201601337R. Epub 2017 May 30. FASEB J. 2017. PMID: 28559441 Free PMC article.
Together, our data suggest that APMAP is a novel regulator of extracellular matrix components, and establish that APMAP is a potential target to mitigate obesity-associated insulin resistance.-Pessentheiner, A. R., Huber, K., Pelzmann, H. J., Prokesch, A., Radner, F. P. W. …
Together, our data suggest that APMAP is a novel regulator of extracellular matrix components, and establish that APMAP is a potential targe …
Deficiency of B vitamins leads to cholesterol-independent atherogenic transformation of the aorta.
Almer G, Opriessnig P, Wolinski H, Sommer G, Diwoky C, Lechleitner M, Kolb D, Bubalo V, Brunner MS, Schwarz AN, Leitinger G, Schoiswohl G, Marsche G, Niedrist T, Schauer S, Oswald W, Groselj-Strele A, Paar M, Cvirn G, Hoefler G, Rechberger GN, Herrmann M, Frank S, Holzapfel GA, Kratky D, Mangge H, Hörl G, Tehlivets O. Almer G, et al. Among authors: wolinski h. Biomed Pharmacother. 2022 Oct;154:113640. doi: 10.1016/j.biopha.2022.113640. Epub 2022 Sep 5. Biomed Pharmacother. 2022. PMID: 36081286 Free article.
The N-terminal region of comparative gene identification-58 (CGI-58) is important for lipid droplet binding and activation of adipose triglyceride lipase.
Gruber A, Cornaciu I, Lass A, Schweiger M, Poeschl M, Eder C, Kumari M, Schoiswohl G, Wolinski H, Kohlwein SD, Zechner R, Zimmermann R, Oberer M. Gruber A, et al. Among authors: wolinski h. J Biol Chem. 2010 Apr 16;285(16):12289-98. doi: 10.1074/jbc.M109.064469. Epub 2010 Feb 17. J Biol Chem. 2010. PMID: 20164531 Free PMC article.
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