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ERG promotes T-acute lymphoblastic leukemia and is transcriptionally regulated in leukemic cells by a stem cell enhancer.
Thoms JA, Birger Y, Foster S, Knezevic K, Kirschenbaum Y, Chandrakanthan V, Jonquieres G, Spensberger D, Wong JW, Oram SH, Kinston SJ, Groner Y, Lock R, MacKenzie KL, Göttgens B, Izraeli S, Pimanda JE. Thoms JA, et al. Among authors: groner y. Blood. 2011 Jun 30;117(26):7079-89. doi: 10.1182/blood-2010-12-317990. Epub 2011 May 2. Blood. 2011. PMID: 21536859 Free article.
A Runx1-Smad6 rheostat controls Runx1 activity during embryonic hematopoiesis.
Knezevic K, Bee T, Wilson NK, Janes ME, Kinston S, Polderdijk S, Kolb-Kokocinski A, Ottersbach K, Pencovich N, Groner Y, de Bruijn M, Göttgens B, Pimanda JE. Knezevic K, et al. Among authors: groner y. Mol Cell Biol. 2011 Jul;31(14):2817-26. doi: 10.1128/MCB.01305-10. Epub 2011 May 16. Mol Cell Biol. 2011. PMID: 21576367 Free PMC article.
RUNX3 negatively regulates CD36 expression in myeloid cell lines.
Puig-Kröger A, Domínguez-Soto A, Martínez-Muñoz L, Serrano-Gómez D, Lopez-Bravo M, Sierra-Filardi E, Fernández-Ruiz E, Ruiz-Velasco N, Ardavín C, Groner Y, Tandon N, Corbí AL, Vega MA. Puig-Kröger A, et al. Among authors: groner y. J Immunol. 2006 Aug 15;177(4):2107-14. doi: 10.4049/jimmunol.177.4.2107. J Immunol. 2006. PMID: 16887969
The novel RUNX3/p33 isoform is induced upon monocyte-derived dendritic cell maturation and downregulates IL-8 expression.
Puig-Kröger A, Aguilera-Montilla N, Martínez-Nuñez R, Domínguez-Soto A, Sánchez-Cabo F, Martín-Gayo E, Zaballos A, Toribio ML, Groner Y, Ito Y, Dopazo A, Corcuera MT, Alonso Martín MJ, Vega MA, Corbí AL. Puig-Kröger A, et al. Among authors: groner y. Immunobiology. 2010 Sep-Oct;215(9-10):812-20. doi: 10.1016/j.imbio.2010.05.018. Epub 2010 Jun 20. Immunobiology. 2010. PMID: 20615577 Free article.
A regulatory interplay between miR-27a and Runx1 during megakaryopoiesis.
Ben-Ami O, Pencovich N, Lotem J, Levanon D, Groner Y. Ben-Ami O, et al. Among authors: groner y. Proc Natl Acad Sci U S A. 2009 Jan 6;106(1):238-43. doi: 10.1073/pnas.0811466106. Epub 2008 Dec 29. Proc Natl Acad Sci U S A. 2009. PMID: 19114653 Free PMC article.
Addiction of t(8;21) and inv(16) acute myeloid leukemia to native RUNX1.
Ben-Ami O, Friedman D, Leshkowitz D, Goldenberg D, Orlovsky K, Pencovich N, Lotem J, Tanay A, Groner Y. Ben-Ami O, et al. Among authors: groner y. Cell Rep. 2013 Sep 26;4(6):1131-43. doi: 10.1016/j.celrep.2013.08.020. Epub 2013 Sep 19. Cell Rep. 2013. PMID: 24055056 Free article.
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