Lock R - Search Results

1

ERG promotes T-acute lymphoblastic leukemia and is transcriptionally regulated in leukemic cells by a stem cell enhancer.

Thoms JA, Birger Y, Foster S, Knezevic K, Kirschenbaum Y, Chandrakanthan V, Jonquieres G, Spensberger D, Wong JW, Oram SH, Kinston SJ, Groner Y, Lock R, MacKenzie KL, Göttgens B, Izraeli S, Pimanda JE. Thoms JA, et al. Among authors: lock r. Blood. 2011 Jun 30;117(26):7079-89. doi: 10.1182/blood-2010-12-317990. Epub 2011 May 2. Blood. 2011. PMID: 21536859 Free article.

2

The nonobese diabetic/severe combined immunodeficient (NOD/SCID) mouse model of childhood acute lymphoblastic leukemia reveals intrinsic differences in biologic characteristics at diagnosis and relapse.

Lock RB, Liem N, Farnsworth ML, Milross CG, Xue C, Tajbakhsh M, Haber M, Norris MD, Marshall GM, Rice AM. Lock RB, et al. Blood. 2002 Jun 1;99(11):4100-8. doi: 10.1182/blood.v99.11.4100. Blood. 2002. PMID: 12010813 Free article.

3

Characterization of childhood acute lymphoblastic leukemia xenograft models for the preclinical evaluation of new therapies.

Liem NL, Papa RA, Milross CG, Schmid MA, Tajbakhsh M, Choi S, Ramirez CD, Rice AM, Haber M, Norris MD, MacKenzie KL, Lock RB. Liem NL, et al. Blood. 2004 May 15;103(10):3905-14. doi: 10.1182/blood-2003-08-2911. Epub 2004 Feb 5. Blood. 2004. PMID: 14764536 Free article.

4

Inactivation of p16INK4a, with retention of pRB and p53/p21cip1 function, in human MRC5 fibroblasts that overcome a telomere-independent crisis during immortalization.

Taylor LM, James A, Schuller CE, Brce J, Lock RB, Mackenzie KL. Taylor LM, et al. J Biol Chem. 2004 Oct 15;279(42):43634-45. doi: 10.1074/jbc.M402388200. Epub 2004 Aug 10. J Biol Chem. 2004. PMID: 15308640 Free article.

5

Dexamethasone resistance in B-cell precursor childhood acute lymphoblastic leukemia occurs downstream of ligand-induced nuclear translocation of the glucocorticoid receptor.

Bachmann PS, Gorman R, Mackenzie KL, Lutze-Mann L, Lock RB. Bachmann PS, et al. Among authors: lock rb. Blood. 2005 Mar 15;105(6):2519-26. doi: 10.1182/blood-2004-05-2023. Epub 2004 Nov 30. Blood. 2005. PMID: 15572593 Free article.

6

FLT-3: a new focus in the understanding of acute leukemia.

Markovic A, MacKenzie KL, Lock RB. Markovic A, et al. Int J Biochem Cell Biol. 2005 Jun;37(6):1168-72. doi: 10.1016/j.biocel.2004.12.005. Epub 2005 Jan 26. Int J Biochem Cell Biol. 2005. PMID: 15778081 Review.

7

RNA loading of leukemic antigens into cord blood-derived dendritic cells for immunotherapy.

Hsu AK, Kerr BM, Jones KL, Lock RB, Hart DN, Rice AM. Hsu AK, et al. Biol Blood Marrow Transplant. 2006 Aug;12(8):855-67. doi: 10.1016/j.bbmt.2006.05.004. Biol Blood Marrow Transplant. 2006. PMID: 16864056 Free article. Clinical Trial.

8

Telomere-driven karyotypic complexity concurs with p16INK4a inactivation in TP53-competent immortal endothelial cells.

Wen VW, Wu K, Baksh S, Hinshelwood RA, Lock RB, Clark SJ, Moore MA, Mackenzie KL. Wen VW, et al. Cancer Res. 2006 Nov 15;66(22):10691-700. doi: 10.1158/0008-5472.CAN-06-0979. Cancer Res. 2006. PMID: 17108106

9

Divergent mechanisms of glucocorticoid resistance in experimental models of pediatric acute lymphoblastic leukemia.

Bachmann PS, Gorman R, Papa RA, Bardell JE, Ford J, Kees UR, Marshall GM, Lock RB. Bachmann PS, et al. Among authors: lock rb. Cancer Res. 2007 May 1;67(9):4482-90. doi: 10.1158/0008-5472.CAN-06-4244. Cancer Res. 2007. PMID: 17483364

10

Activity of vincristine, L-ASP, and dexamethasone against acute lymphoblastic leukemia is enhanced by the BH3-mimetic ABT-737 in vitro and in vivo.

Kang MH, Kang YH, Szymanska B, Wilczynska-Kalak U, Sheard MA, Harned TM, Lock RB, Reynolds CP. Kang MH, et al. Blood. 2007 Sep 15;110(6):2057-66. doi: 10.1182/blood-2007-03-080325. Epub 2007 May 29. Blood. 2007. PMID: 17536015 Free article.

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