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Using polymorphisms in FKBP5 to define biologically distinct subtypes of posttraumatic stress disorder: evidence from endocrine and gene expression studies.
Mehta D, Gonik M, Klengel T, Rex-Haffner M, Menke A, Rubel J, Mercer KB, Pütz B, Bradley B, Holsboer F, Ressler KJ, Müller-Myhsok B, Binder EB. Mehta D, et al. Among authors: mercer kb. Arch Gen Psychiatry. 2011 Sep;68(9):901-10. doi: 10.1001/archgenpsychiatry.2011.50. Epub 2011 May 2. Arch Gen Psychiatry. 2011. PMID: 21536970 Free PMC article.
Allele-specific FKBP5 DNA demethylation mediates gene-childhood trauma interactions.
Klengel T, Mehta D, Anacker C, Rex-Haffner M, Pruessner JC, Pariante CM, Pace TW, Mercer KB, Mayberg HS, Bradley B, Nemeroff CB, Holsboer F, Heim CM, Ressler KJ, Rein T, Binder EB. Klengel T, et al. Among authors: mercer kb. Nat Neurosci. 2013 Jan;16(1):33-41. doi: 10.1038/nn.3275. Epub 2012 Dec 2. Nat Neurosci. 2013. PMID: 23201972 Free PMC article.
Childhood maltreatment is associated with distinct genomic and epigenetic profiles in posttraumatic stress disorder.
Mehta D, Klengel T, Conneely KN, Smith AK, Altmann A, Pace TW, Rex-Haffner M, Loeschner A, Gonik M, Mercer KB, Bradley B, Müller-Myhsok B, Ressler KJ, Binder EB. Mehta D, et al. Among authors: mercer kb. Proc Natl Acad Sci U S A. 2013 May 14;110(20):8302-7. doi: 10.1073/pnas.1217750110. Epub 2013 Apr 29. Proc Natl Acad Sci U S A. 2013. PMID: 23630272 Free PMC article.
FKBP5 and attention bias for threat: associations with hippocampal function and shape.
Fani N, Gutman D, Tone EB, Almli L, Mercer KB, Davis J, Glover E, Jovanovic T, Bradley B, Dinov ID, Zamanyan A, Toga AW, Binder EB, Ressler KJ. Fani N, et al. Among authors: mercer kb. JAMA Psychiatry. 2013 Apr;70(4):392-400. doi: 10.1001/2013.jamapsychiatry.210. JAMA Psychiatry. 2013. PMID: 23407841 Free PMC article.
Sex dependent influence of a functional polymorphism in steroid 5-α-reductase type 2 (SRD5A2) on post-traumatic stress symptoms.
Gillespie CF, Almli LM, Smith AK, Bradley B, Kerley K, Crain DF, Mercer KB, Weiss T, Phifer J, Tang Y, Cubells JF, Binder EB, Conneely KN, Ressler KJ. Gillespie CF, et al. Among authors: mercer kb. Am J Med Genet B Neuropsychiatr Genet. 2013 Apr;162B(3):283-292. doi: 10.1002/ajmg.b.32147. Epub 2013 Mar 15. Am J Med Genet B Neuropsychiatr Genet. 2013. PMID: 23505265 Free PMC article.
A genome-wide identified risk variant for PTSD is a methylation quantitative trait locus and confers decreased cortical activation to fearful faces.
Almli LM, Stevens JS, Smith AK, Kilaru V, Meng Q, Flory J, Abu-Amara D, Hammamieh R, Yang R, Mercer KB, Binder EB, Bradley B, Hamilton S, Jett M, Yehuda R, Marmar CR, Ressler KJ. Almli LM, et al. Among authors: mercer kb. Am J Med Genet B Neuropsychiatr Genet. 2015 Jul;168B(5):327-36. doi: 10.1002/ajmg.b.32315. Epub 2015 May 18. Am J Med Genet B Neuropsychiatr Genet. 2015. PMID: 25988933 Free PMC article.
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