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Page 1
Cardiac HDAC6 catalytic activity is induced in response to chronic hypertension.
Lemon DD, Horn TR, Cavasin MA, Jeong MY, Haubold KW, Long CS, Irwin DC, McCune SA, Chung E, Leinwand LA, McKinsey TA. Lemon DD, et al. Among authors: irwin dc. J Mol Cell Cardiol. 2011 Jul;51(1):41-50. doi: 10.1016/j.yjmcc.2011.04.005. Epub 2011 Apr 23. J Mol Cell Cardiol. 2011. PMID: 21539845 Free PMC article.
Mice deficient in galectin-1 exhibit attenuated physiological responses to chronic hypoxia-induced pulmonary hypertension.
Case D, Irwin D, Ivester C, Harral J, Morris K, Imamura M, Roedersheimer M, Patterson A, Carr M, Hagen M, Saavedra M, Crossno J Jr, Young KA, Dempsey EC, Poirier F, West J, Majka S. Case D, et al. Am J Physiol Lung Cell Mol Physiol. 2007 Jan;292(1):L154-64. doi: 10.1152/ajplung.00192.2006. Epub 2006 Sep 1. Am J Physiol Lung Cell Mol Physiol. 2007. PMID: 16951131 Free article.
Selective class I histone deacetylase inhibition suppresses hypoxia-induced cardiopulmonary remodeling through an antiproliferative mechanism.
Cavasin MA, Demos-Davies K, Horn TR, Walker LA, Lemon DD, Birdsey N, Weiser-Evans MC, Harral J, Irwin DC, Anwar A, Yeager ME, Li M, Watson PA, Nemenoff RA, Buttrick PM, Stenmark KR, McKinsey TA. Cavasin MA, et al. Among authors: irwin dc. Circ Res. 2012 Mar 2;110(5):739-48. doi: 10.1161/CIRCRESAHA.111.258426. Epub 2012 Jan 26. Circ Res. 2012. PMID: 22282194 Free PMC article.
Selective depletion of vascular EC-SOD augments chronic hypoxic pulmonary hypertension.
Nozik-Grayck E, Woods C, Taylor JM, Benninger RK, Johnson RD, Villegas LR, Stenmark KR, Harrison DG, Majka SM, Irwin D, Farrow KN. Nozik-Grayck E, et al. Am J Physiol Lung Cell Mol Physiol. 2014 Dec 1;307(11):L868-76. doi: 10.1152/ajplung.00096.2014. Epub 2014 Oct 17. Am J Physiol Lung Cell Mol Physiol. 2014. PMID: 25326578 Free PMC article.
Cardiomyocyte-Specific Long Noncoding RNA Regulates Alternative Splicing of the Triadin Gene in the Heart.
Zhao Y, Riching AS, Knight WE, Chi C, Broadwell LJ, Du Y, Abdel-Hafiz M, Ambardekar AV, Irwin DC, Proenza C, Xu H, Leinwand LA, Walker LA, Woulfe KC, Bristow MR, Buttrick PM, Song K. Zhao Y, et al. Among authors: irwin dc. Circulation. 2022 Aug 30;146(9):699-714. doi: 10.1161/CIRCULATIONAHA.121.058017. Epub 2022 Jul 18. Circulation. 2022. PMID: 35862102 Free PMC article.
Neonatal lung side population cells demonstrate endothelial potential and are altered in response to hyperoxia-induced lung simplification.
Irwin D, Helm K, Campbell N, Imamura M, Fagan K, Harral J, Carr M, Young KA, Klemm D, Gebb S, Dempsey EC, West J, Majka S. Irwin D, et al. Am J Physiol Lung Cell Mol Physiol. 2007 Oct;293(4):L941-51. doi: 10.1152/ajplung.00054.2007. Epub 2007 Aug 10. Am J Physiol Lung Cell Mol Physiol. 2007. PMID: 17693487 Free article.
Hemoglobin-induced lung vascular oxidation, inflammation, and remodeling contribute to the progression of hypoxic pulmonary hypertension and is attenuated in rats with repeated-dose haptoglobin administration.
Irwin DC, Baek JH, Hassell K, Nuss R, Eigenberger P, Lisk C, Loomis Z, Maltzahn J, Stenmark KR, Nozik-Grayck E, Buehler PW. Irwin DC, et al. Free Radic Biol Med. 2015 May;82:50-62. doi: 10.1016/j.freeradbiomed.2015.01.012. Epub 2015 Feb 2. Free Radic Biol Med. 2015. PMID: 25656991 Free PMC article.
Vascular Adaptation of the Right Ventricle in Experimental Pulmonary Hypertension.
Graham BB, Kumar R, Mickael C, Kassa B, Koyanagi D, Sanders L, Zhang L, Perez M, Hernandez-Saavedra D, Valencia C, Dixon K, Harral J, Loomis Z, Irwin D, Nemkov T, D'Alessandro A, Stenmark KR, Tuder RM. Graham BB, et al. Am J Respir Cell Mol Biol. 2018 Oct;59(4):479-489. doi: 10.1165/rcmb.2018-0095OC. Am J Respir Cell Mol Biol. 2018. PMID: 29851508 Free PMC article.
Contribution of fatty acid oxidation to the pathogenesis of pulmonary hypertension.
Lee MH, Sanders L, Kumar R, Hernandez-Saavedra D, Yun X, Ford JA, Perez MJ, Mickael C, Gandjeva A, Koyanagi DE, Harral JW, Irwin DC, Kassa B, Eckel RH, Shimoda LA, Graham BB, Tuder RM. Lee MH, et al. Among authors: irwin dc. Am J Physiol Lung Cell Mol Physiol. 2022 Sep 1;323(3):L355-L371. doi: 10.1152/ajplung.00039.2022. Epub 2022 Jun 28. Am J Physiol Lung Cell Mol Physiol. 2022. PMID: 35763400 Free PMC article.
77 results