Murphy SE - Search Results

1

Common polymorphisms in FMO1 are associated with nicotine dependence.

Hinrichs AL, Murphy SE, Wang JC, Saccone S, Saccone N, Steinbach JH, Goate A, Stevens VL, Bierut LJ. Hinrichs AL, et al. Among authors: murphy se. Pharmacogenet Genomics. 2011 Jul;21(7):397-402. doi: 10.1097/FPC.0b013e328346886f. Pharmacogenet Genomics. 2011. PMID: 21540762 Free PMC article.

2

The contribution of common CYP2A6 alleles to variation in nicotine metabolism among European-Americans.

Bloom J, Hinrichs AL, Wang JC, von Weymarn LB, Kharasch ED, Bierut LJ, Goate A, Murphy SE. Bloom J, et al. Among authors: murphy se. Pharmacogenet Genomics. 2011 Jul;21(7):403-16. doi: 10.1097/FPC.0b013e328346e8c0. Pharmacogenet Genomics. 2011. PMID: 21597399 Free PMC article.

3

Effects upon in-vivo nicotine metabolism reveal functional variation in FMO3 associated with cigarette consumption.

Bloom AJ, Murphy SE, Martinez M, von Weymarn LB, Bierut LJ, Goate A. Bloom AJ, et al. Among authors: murphy se. Pharmacogenet Genomics. 2013 Feb;23(2):62-8. doi: 10.1097/FPC.0b013e32835c3b48. Pharmacogenet Genomics. 2013. PMID: 23211429 Free PMC article.

4

The contribution of common UGT2B10 and CYP2A6 alleles to variation in nicotine glucuronidation among European Americans.

Bloom AJ, von Weymarn LB, Martinez M, Bierut LJ, Goate A, Murphy SE. Bloom AJ, et al. Among authors: murphy se. Pharmacogenet Genomics. 2013 Dec;23(12):706-16. doi: 10.1097/FPC.0000000000000011. Pharmacogenet Genomics. 2013. PMID: 24192532 Free PMC article.

5

CYP2B6 non-coding variation associated with smoking cessation is also associated with differences in allelic expression, splicing, and nicotine metabolism independent of common amino-acid changes.

Bloom AJ, Martinez M, Chen LS, Bierut LJ, Murphy SE, Goate A. Bloom AJ, et al. Among authors: murphy se. PLoS One. 2013 Nov 15;8(11):e79700. doi: 10.1371/journal.pone.0079700. eCollection 2013. PLoS One. 2013. PMID: 24260284 Free PMC article.

6

Nicotine dependence is associated with functional variation in FMO3, an enzyme that metabolizes nicotine in the brain.

Teitelbaum AM, Murphy SE, Akk G, Baker TB, Germann A, von Weymarn LB, Bierut LJ, Goate A, Kharasch ED, Bloom AJ. Teitelbaum AM, et al. Among authors: murphy se. Pharmacogenomics J. 2018 Jan;18(1):136-143. doi: 10.1038/tpj.2016.92. Epub 2017 Mar 14. Pharmacogenomics J. 2018. PMID: 28290528 Free PMC article.

7

Use of a predictive model derived from in vivo endophenotype measurements to demonstrate associations with a complex locus, CYP2A6.

Bloom AJ, Harari O, Martinez M, Madden PA, Martin NG, Montgomery GW, Rice JP, Murphy SE, Bierut LJ, Goate A. Bloom AJ, et al. Among authors: murphy se. Hum Mol Genet. 2012 Jul 1;21(13):3050-62. doi: 10.1093/hmg/dds114. Epub 2012 Mar 26. Hum Mol Genet. 2012. PMID: 22451501 Free PMC article.

8

A compensatory effect upon splicing results in normal function of the CYP2A6*14 allele.

Bloom AJ, Harari O, Martinez M, Zhang X, McDonald SA, Murphy SE, Goate A. Bloom AJ, et al. Among authors: murphy se. Pharmacogenet Genomics. 2013 Mar;23(3):107-16. doi: 10.1097/FPC.0b013e32835caf7d. Pharmacogenet Genomics. 2013. PMID: 23292114 Free PMC article.

9

Predicting nicotine metabolism across ancestries using genotypes.

Baurley JW, Bergen AW, Ervin CM, Park SL, Murphy SE, McMahan CS. Baurley JW, et al. Among authors: murphy se. BMC Genomics. 2022 Sep 21;23(1):663. doi: 10.1186/s12864-022-08884-z. BMC Genomics. 2022. PMID: 36131240 Free PMC article.

10

Multiethnic Prediction of Nicotine Biomarkers and Association With Nicotine Dependence.

Bergen AW, McMahan CS, McGee S, Ervin CM, Tindle HA, Le Marchand L, Murphy SE, Stram DO, Patel YM, Park SL, Baurley JW. Bergen AW, et al. Among authors: murphy se. Nicotine Tob Res. 2021 Nov 5;23(12):2162-2169. doi: 10.1093/ntr/ntab124. Nicotine Tob Res. 2021. PMID: 34313775 Free PMC article.

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